ChemicalBook > CAS DataBase List > Orphanin FQ (1-11)
Orphanin FQ (1-11)
- Product Name
- Orphanin FQ (1-11)
- CAS No.
- 178249-41-7
- Chemical Name
- Orphanin FQ (1-11)
- Synonyms
- Orphanin FQ (1-11);L-Alanine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-
- CBNumber
- CB52518827
- Molecular Formula
- C49H75N15O14
- Formula Weight
- 1098.21
- MOL File
- 178249-41-7.mol
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Orphanin FQ (1-11) Property
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble to 2 mg/ml in 20% acetonitrile / water
- form
- Powder
- pka
- 3.32±0.10(Predicted)
- color
- White to off-white
- Sequence
- H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-OH
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N-Bromosuccinimide Price
ApexBio Technology
- Product number
- B5497
- Product name
- OrphaninFQ(1-11)
- Packaging
- 1mg
- Price
- $171
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0002674
- Product name
- ORPHANIN FQ/NOCICEPTIN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $636.7
- Updated
- 2021/12/16
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Orphanin FQ (1-11) Chemical Properties,Usage,Production
Uses
Orphanin FQ(1-11), a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) is analgesic in CD-1 mice[1][2].
References
[1] Reinscheid RK, et al. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem. 1996;271(24):14163-14168. DOI:10.1074/jbc.271.24.14163
[2] Rossi GC, et al. Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J Pharmacol Exp Ther. 1997;282(2):858-865. PMID:9262352
Orphanin FQ (1-11) Preparation Products And Raw materials
Raw materials
Preparation Products
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