(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone
- Product Name
- (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone
- CAS No.
- 346673-06-1
- Chemical Name
- (5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone
- Synonyms
- CAY10598;TCS 2510;CAY10598, EP4 agonist;(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone;2-Pyrrolidinone, 5-[(3S)-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-, (5R)-
- CBNumber
- CB52518887
- Molecular Formula
- C21H29N5O2
- Formula Weight
- 383
- MOL File
- 346673-06-1.mol
(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone Property
- Boiling point:
- 632.0±65.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
- form
- Powder
- pka
- 5.07±0.10(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H350May cause cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 13281
- Product name
- CAY10598
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $96
- Updated
- 2024/03/01
- Product number
- 13281
- Product name
- CAY10598
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $134
- Updated
- 2024/03/01
- Product number
- 13281
- Product name
- CAY10598
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $526
- Updated
- 2024/03/01
- Product number
- 13281
- Product name
- CAY10598
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $954
- Updated
- 2024/03/01
- Product number
- 4069
- Product name
- TCS2510
- Purity
- ≥98%(HPLC)
- Packaging
- 1
- Price
- $229
- Updated
- 2021/12/16
(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone Chemical Properties,Usage,Production
Uses
TCS 2510 is a selective agonist of EP4.
in vivo
TCS 2510 (0.1~10 mg/kg; p.o.) produces a dose-dependent elevation in plasma glucagon like peptide 1 levels in fasted mice measured 15 min after compound administration[1].
TCS 2510 (10 mg/kg; p.o.) increases plasma glucagon like peptide 1 levels up to 8-fold over the basal hormone levels[1].
TCS 2510 (1~10 mg/kg; p.o) affords a significant elevation in plasma glucagon like peptide 2 levels[1]
| Animal Model: | Mice[1] |
| Dosage: | 0.1~10 mg/kg |
| Administration: | P.o. |
| Result: | Produced a dose-dependent elevation in plasma glucagon like peptide 1 levels in fasted mice measured 15 min after compound administration. |
| Animal Model: | Mice[1] |
| Dosage: | 10 mg/kg |
| Administration: | P.o. |
| Result: | Increased plasma glucagon like peptide 1 levels up to 8-fold over the basal hormone levels. |
| Animal Model: | Mice[1] |
| Dosage: | 1~10 mg/kg |
| Administration: | P.o. |
| Result: | Afforded a significant elevation in plasma glucagon like peptide 2 levels. |
storage
Store at -20°C
(5R)-5-[(3S)-3-Hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone Preparation Products And Raw materials
Raw materials
Preparation Products
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