ChemicalBook > CAS DataBase List > 2-Bromo-3-fluoro-6-picoline

2-Bromo-3-fluoro-6-picoline

Product Name
2-Bromo-3-fluoro-6-picoline
CAS No.
374633-36-0
Chemical Name
2-Bromo-3-fluoro-6-picoline
Synonyms
2-bromo-3-fluoro-6-methylpyridine;2-Bromo-3-fL;uoro-6-methyL;6-Bromo-5-fluoro-2-picoline;2-BROMO-3-FLUORO-6-PICOLINE;Pyridine, 2-bromo-3-fluoro-6-methyl-;2-Bromo-3-fluoro-6-methylpyridine,98%;2-BROMO-3-FLUORO-6-PICOLINE ISO 9001:2015 REACH
CBNumber
CB5252466
Molecular Formula
C6H5BrFN
Formula Weight
190.01
MOL File
374633-36-0.mol
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2-Bromo-3-fluoro-6-picoline Property

Boiling point:
185.6±35.0 °C(Predicted)
Density 
1.592±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
-0.91±0.10(Predicted)
form 
Solid
InChIKey
KKVUMKHUMBXLMH-UHFFFAOYSA-N
CAS DataBase Reference
374633-36-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
AGN00010
Product name
2-Bromo-3-fluoro-6-methylpyridine
Purity
Aldrich
Packaging
1g
Price
$320
Updated
2024/03/01
Alfa Aesar
Product number
H64900
Product name
2-Bromo-3-fluoro-6-methylpyridine, 98%
Packaging
1g
Price
$25.7
Updated
2023/06/20
Alfa Aesar
Product number
H64900
Product name
2-Bromo-3-fluoro-6-methylpyridine, 98%
Packaging
5g
Price
$106
Updated
2023/06/20
Alfa Aesar
Product number
H64900
Product name
2-Bromo-3-fluoro-6-methylpyridine, 98%
Packaging
25g
Price
$391
Updated
2021/12/16
TRC
Product number
B685188
Product name
2-Bromo-3-fluoro-6-picoline
Packaging
250mg
Price
$55
Updated
2021/12/16
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2-Bromo-3-fluoro-6-picoline Chemical Properties,Usage,Production

Synthesis

3-Amino-2-bromo-6-methylpyridine or 4-amino-2-bromo-6-methylpyridine (25.20 g, 134.73 mmol) was added to a mixture of water (78.1 mL) and conc. HCl (12.8 mL, 350.30 mmol), and then the mixture was cooled to 0 ℃. To it, sodium nitrite (18.6 g,269.46 mmol) was added portion-wise with stirring over 20 min while keeping the reaction temperature between –5 ℃and 0 ℃. After 10 min, 65 per cent hexafluorophosphoric acid solution (43.26 g, 296.41 mmol) was added dropwise with cooling, at which point many precipitates were formed. The precipitates were collected by filtration using a glass filter funnel, washed with cold water (2 × 50 mL) and diethyl ether (100 mL), and then dried in the air for 48 h. The solid was slowly heated to 100 ℃ (very exothermic), and a dark, oily material was formed after 10 min. The oil was basified with diluted NaOH solution to pH~10 and extracted with CH2Cl2 (2 × 150 mL). The combined organic layer was dried over anhydrous Na2SO4, filtered, and evaporated to dryness under reduced pressure. The residue was purified by MPLC on neutral alumina using hexane/EtOAc (10:1) as an eluent to afford 2-Bromo-3-fluoro-6-picoline.

2-Bromo-3-fluoro-6-picoline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-3-fluoro-6-picoline Suppliers

Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1889
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55
ShangHai DEMO Chemical Co.,Ltd
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400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
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China
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2572
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57
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
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Shijiazhuang Sdyano Fine Chemical Co., Ltd.
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0311-89250318 031166536426
Fax
4000311741
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master@sjzsdyn.com
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China
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Beijing Mediking Biopharm Co., Ltd
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010-81769521,89753524,81760121 15901403431
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+86-10-81769652
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sales01@mediking.cn
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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sales@capotchem.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
Fax
86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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9976
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
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China
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9414
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66
Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
Fax
021-50795055
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sales@accelachem.com
Country
China
ProdList
11655
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64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
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View Lastest Price from 2-Bromo-3-fluoro-6-picoline manufacturers

Dideu Industries Group Limited
Product
2-BROMO-3-FLUORO-6-PICOLINE 374633-36-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-BROMO-3-FLUORO-6-PICOLINE 374633-36-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Career Henan Chemical Co
Product
2-BROMO-3-FLUORO-6-PICOLINE 374633-36-0
Price
US $3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-10