ChemicalBook > CAS DataBase List > 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Product Name
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS No.
133627-17-5
Chemical Name
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms
BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
CBNumber
CB52539709
Molecular Formula
C14H14N4O
Formula Weight
254.29
MOL File
133627-17-5.mol
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Property

Melting point:
212-214℃ (1,2-dichloroethane )
Boiling point:
389.8±42.0 °C(Predicted)
Density 
1.224±0.06 g/cm3(Predicted)
pka
12.05±0.20(Predicted)
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Safety

HS Code 
2933997500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1460725
Product name
Nevirapine Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15MG
Price
$1300
Updated
2024/03/01
TRC
Product number
B399700
Product name
BIRH414
Packaging
100mg
Price
$1510
Updated
2021/12/16
Usbiological
Product number
162856
Product name
BIRH 414
Packaging
10mg
Price
$502
Updated
2021/12/16
AvaChem
Product number
3831
Product name
Nevirapine Impurity A
Packaging
25mg
Price
$575
Updated
2021/12/16
AvaChem
Product number
3831
Product name
Nevirapine Impurity A
Packaging
5mg
Price
$175
Updated
2021/12/16
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties,Usage,Production

Uses

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Suppliers

Canada 1 China 23 India 3 United Kingdom 1 United States 4 Global 32
Toronto Research Chemicals
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Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
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Advantage
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133627-17-5, 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-oneRelated Search:


  • Nevirapine Related CoMpound A
  • Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one)
  • BIRH 414
  • 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
  • Nevirapine EP Impurity A
  • BIRH 414 BS
  • Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one}
  • 11-Ethyl-4-methyl-5,11-dihydro-6H-d
  • 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl-
  • Nevirapine Related Compound A (15 mg)
  • Nevirapine EP Impurity A/ Nevirapine Related Compound A
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one
  • Nevirapine impurity Ⅱ {11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′ -e][1,4] diazepin-6-one}
  • Nevirapine USP Related Compound A
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 11-Ethyl-4-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 133627-17-5
  • 25429
  • Pharmaceuticals, Intermediates & Fine Chemicals