ChemicalBook > CAS DataBase List > PHA-543613 Dihydrochloride
PHA-543613 Dihydrochloride
- Product Name
- PHA-543613 Dihydrochloride
- CAS No.
- 478148-58-2
- Chemical Name
- PHA-543613 Dihydrochloride
- Synonyms
- PHA 543613E;PHA-543613 Dihydrochloride;PHA-543613 Dihydrochloride DISCONTINUED;N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxaMide Dihydrochloride
- CBNumber
- CB52545557
- Molecular Formula
- C15H17N3O2
- Formula Weight
- 271.31438
- MOL File
- 478148-58-2.mol
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PHA-543613 Dihydrochloride Property
- Melting point:
- >300?C
- storage temp.
- Refrigerator
- solubility
- DMSO, Methanol
- form
- Solid
- color
- Tan
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N-Bromosuccinimide Price
Usbiological
- Product number
- 019334
- Product name
- PHA-543613 Dihydrochloride
- Packaging
- 10mg
- Price
- $460
- Updated
- 2021/12/16
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PHA-543613 Dihydrochloride Chemical Properties,Usage,Production
Chemical Properties
Tan Solid
Uses
PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays.
PHA-543613 Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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