ChemicalBook > CAS DataBase List > Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-

Product Name: Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-
CAS No.: 362665-56-3
Chemical Name: Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-
Synonyms: Tilolison;Pitolisomt;PITOLISANT;Tirolisant;Tiprolisant;Pitolisant (BF2.649);Tiprolisant Pitolisant;TIPROLISANT;BF-2649;BF 2.649;Chlorophenyl)propoxy)propyl)piperidine;3-(4-Chlorophenyl)propyl 3-piperidinopropyl ether
CBNumber: CB52563438
Molecular Formula: C17H26ClNO
Formula Weight: 295.85
MOL File: 362665-56-3.mol

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Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]- Property

Boiling point:: 398.7±32.0 °C(Predicted)
Density: 1.056
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO
form: Powder
pka: 9.41±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FP168175
Product name: Pitolisant
Packaging: 50mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP168175
Product name: Pitolisant
Packaging: 100mg
Price: $300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP168175
Product name: Pitolisant
Packaging: 250mg
Price: $450
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611361
Product name: Pitolisant
Packaging: 100mg
Price: $606.9
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP168175
Product name: Pitolisant
Packaging: 500mg
Price: $650
Updated: 2021/12/16

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Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]- Chemical Properties,Usage,Production

Uses

Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor. Pitolisant is also used in the treatment of patients with narcolepsy, excessive daytime sleepiness, cataplexy, disturbed nocturnal sleep, hypnagogic hallucinations and sleep paralysis

Definition

ChEBI: Pitolisant is an organochlorine compound.

in vivo

The administration of Pitolisantat a single dose of 10 mg/kg 30 min before a single dose of Olanzapine (2 mg/kg b.w.) also significantly affects immobility time in the FST. Subsequent administration of the aforementioned drug sequence in mice statistically significantly increases the duration of immobility in comparison to the time determined in the control group in the FST. It decreased locomotor activity as well. In contrast, the results obtained in subchronic treatment after fifteen administrations of both drugs (Pitolisant 10 mg/kg b.w., and after 30 min Olanzapine 2 mg/kg b.w., and again after 4 h Olanzapine 2 mg/kg b.w.) show that the administration of Pitolisant followed by that of Olanzapine equalized the locomotor activity in mice; in comparison to the level of motility in the control group, to which only Pitolisant is administered. More importantly, this combination of drugs significantly reduces immobility time to the level obtained in the control group in the forced swim test in mice [one-way ANOVA; F_(3,20)=4.226,P=0.0181]^[2]. Rats given Pitolisant (10 mg/kg) during the conditioning phase stayed 502±94 s on the paired texture, a value not statistically different from that of controls, indicating that Pitolisant did not support place preference^[3].

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]- manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pitolisant 362665-56-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pitolisant 362665-56-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]- 362665-56-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg
Release date: 2019-08-31

362665-56-3, Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-Related Search:

Tiprolisant oxalate 1-[3-[3-(4-Chlorophenyl)propoxy]propyl]-piperidinehydrochloride

Piperidine, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-

PITOLISANT

1-[3-[3-(4-Chlorophenyl)propoxy]propyl]piperidine

3-(4-Chlorophenyl)propyl 3-piperidinopropyl ether

Tiprolisant

Tirolisant

Pitolisant (BF2.649)

TIPROLISANT;BF-2649;BF 2.649

Tiprolisant Pitolisant

Tilolison

Pitolisomt

Chlorophenyl)propoxy)propyl)piperidine

362665-56-3

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