ChemicalBook > CAS DataBase List > ATN-224

ATN-224

Product Name
ATN-224
CAS No.
649749-10-0
Chemical Name
ATN-224
Synonyms
ATN-224;WTX-101);ATN 224,ATN224;Choline tetrathiomolybdate;Bis(choline)tetrathioMolybdate;ATN-224 (Choline tetrathiomolybdate;CHOLINE TETRATHIOMOLYBDATE;WTX-101;WTX 101;WTX101;2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate;bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide
CBNumber
CB52582927
Molecular Formula
C5H14MoNOS4-
Formula Weight
328.36
MOL File
649749-10-0.mol
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ATN-224 Property

storage temp. 
Store at -20°C
solubility 
DMSO:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:PBS (pH 7.2):0.5(Max Conc. mg/mL);1.16(Max Conc. mM)
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3409
Product name
ATN-224
Purity
≥95% (elemental analysis)
Packaging
5MG
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
SML3409
Product name
ATN-224
Purity
≥95% (elemental analysis)
Packaging
25MG
Price
$327
Updated
2024/03/01
Cayman Chemical
Product number
23553
Product name
ATN-224
Purity
≥95%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
23553
Product name
ATN-224
Purity
≥95%
Packaging
5mg
Price
$214
Updated
2024/03/01
Cayman Chemical
Product number
23553
Product name
ATN-224
Purity
≥95%
Packaging
10mg
Price
$365
Updated
2024/03/01
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ATN-224 Chemical Properties,Usage,Production

Description

ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1; IC50s = 2.91 and 3.51 μM in human and mouse blood cells, respectively, in vitro). ATN-224 reduces the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells (EC50s = 5-6 nM) and human diffuse large B cell lymphoma cell lines (EC50s = 9.73-105.61 nM) independently of Bcl-2 and Bcl-xL. In vivo, ATN-224 (0.7 mg/kg) chelates copper to stabilize an antitumor viral vector, enhancing its efficacy against lung metastases in mice. It also inhibits angiogenesis in a mouse model (IC50s = 1.50-3 mg/kg via gavage).

ATN-224 Preparation Products And Raw materials

Raw materials

Preparation Products

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ATN-224 Suppliers

China 28 India 1 United Kingdom 1 United States 4 Global 34
Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
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+86-21-57758967
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sales@boylechem.com
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China
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BeiJing Hwrk Chemicals Limted
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0757-86329057 18501085097
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010-89508210
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sales3.gd@hwrkchemical.com
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Lanzhou Angeli Biochemical Technology Co., Ltd.
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0931-8235634 13321316780
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+86(931) 4873122
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1455540579@qq.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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Tianjin heowns Biochemical Technology Co., Ltd.
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400-6387771-6039 18920564737
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sales@heowns.com
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Career Henan Chemica Co
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+86-0371-86658258 15093356674;
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0371-86658258
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laboratory@coreychem.com
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Hubei Jusheng Technology Co.,Ltd.
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18871490254
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027-59599243
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linda@hubeijusheng.com
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DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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Guangdong Wengjiang Chemical Reagent Co., Ltd.
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0751-2886766 13927870850
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0751-2886756
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3001267247@qq.com
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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Shanghai Zeye Biotechnology Co., Ltd.
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021-61998551 13122364865
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sale1@shzysw.net
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Absin Bioscience Inc.
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021-38015121 15000105423
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chenjw@absin.cn
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Changzhou Furuisi Biotechnology Co., Ltd
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0519-85524369
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Bide Pharmatech Ltd.
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400-1647117 15221909166
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product02@bidepharm.com
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InvivoChem
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13549236410
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sales@invivochem.cn
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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18621169109
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market03@meryer.com
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Qiyuan (Guangdong) Pharmaceutical Chemical Co., Ltd.
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Shaanxi Xihua Chemical Industry Co., Ltd
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17691182729 15529505138
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1021@dideu.com
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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Shanghai Acmec Biochemical Technology Co., Ltd.
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+undefined18621343501
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product@acmec-e.com
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LEAPCHEM CO., LTD.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Guangzhou Weijia Technology Co., Ltd.
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Shanghai Yuda Industrial Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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649749-10-0, ATN-224Related Search:


  • ATN-224
  • Bis(choline)tetrathioMolybdate
  • ATN-224 (Choline tetrathiomolybdate
  • WTX-101)
  • Choline tetrathiomolybdate
  • CHOLINE TETRATHIOMOLYBDATE;WTX-101;WTX 101;WTX101
  • bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide
  • 2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate
  • ATN 224,ATN224
  • 649749-10-0
  • 2C5H14NOMoS4
  • C10H32MoN2O2S4