O-ButylhydroxylaMine Hydrochloride
- Product Name
- O-ButylhydroxylaMine Hydrochloride
- CAS No.
- 4490-82-8
- Chemical Name
- O-ButylhydroxylaMine Hydrochloride
- Synonyms
- O-butylhydroxylamine HCl;n-Butoxyamine hydrochloride;n-butyloxyamine hydrochloride;O-ButylhydroxylaMine Hydrochloride
- CBNumber
- CB52594535
- Molecular Formula
- C4H12ClNO
- Formula Weight
- 125.59718
- MOL File
- 4490-82-8.mol
O-ButylhydroxylaMine Hydrochloride Property
- Melting point:
- 157.0 to 161.0 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- color
- White to Almost white
Safety
- HS Code
- 2928009090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B5686
- Product name
- O-Butylhydroxylamine Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 1g
- Price
- $58
- Updated
- 2025/07/31
- Product number
- B5686
- Product name
- O-Butylhydroxylamine Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $175
- Updated
- 2025/07/31
- Product number
- B943423
- Product name
- O-Butylhydroxylamine Hydrochloride
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CS-0106180
- Product name
- O-Butylhydroxylamine Hydrochloride
- Purity
- ≥98.0%
- Packaging
- 10g
- Price
- $217
- Updated
- 2021/12/16
- Product number
- V6009
- Product name
- O-ButylhydroxylamineHCl
- Packaging
- 5g
- Price
- $275
- Updated
- 2021/12/16
O-ButylhydroxylaMine Hydrochloride Chemical Properties,Usage,Production
Synthesis
51951-28-1
4490-82-8
1. 500 mg of hydroxyphthalimide (Aldrich) was dissolved in 5 mL of dimethylformamide (DMF) under argon protection. 2. 0.38 mL of 1-iodobutane (Aldrich) and 0.5 mL of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU, Aldrich) were added sequentially and slowly. 3. The reaction mixture was stirred at 60 °C for 2 h and subsequently cooled to room temperature. 4. The reaction was terminated by addition of 2 N hydrochloric acid solution and the reaction solution was diluted with 20 mL of ethyl acetate. 5. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. 6. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to give 635 mg of the target compound (95% yield). 7. The above compound was dissolved in 5 mL of dichloromethane and 0.12 mL of methylhydrazine (TCI) was added slowly at 0 °C. 8. The reaction solution was stirred at room temperature for 2 hours and then cooled to 0°C again. 9. The resulting solid was collected by filtration and 1 mL of 4 M dioxane hydrochloride solution (Aldrich) was added to the filtrate, which was filtered and dried to give 257 mg solid (100% yield). 10. 13 mg of the above solid was dissolved with 44 mg of SAC-0906 in 1 mL of pyridine (Aldrich) under argon protection and stirred at 80 °C for 4 hours. 11. The reaction solution was cooled to room temperature, acidified with 2 N hydrochloric acid solution and extracted with 20 mL of ether. 12. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. 13. The residue was purified by silica gel column chromatography using ethyl acetate/hexane (1:5) as eluent to afford O-butylhydroxylamine hydrochloride SAC-1015 (44 mg, 88% yield). 14. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ 5.91-5.76 (m, 2H), 5.34-5.33 (m, 1H), 5.28-5.25 (m, 1H), 5.15 (m, 1H), 4.25-4.10 (m, 3H), 4.02-3.97 (m, 2H), 3.59-3.48 (m, 1H), 3.59-3.48 (m, 2H). (m, 1H), 2.42-0.60 (m, 42H).
References
[1] Patent: US2014/378399, 2014, A1. Location in patent: Paragraph 0100
[2] Farmaco, Edizione Scientifica, 1987, vol. 42, # 10, p. 697 - 708
[3] European Journal of Medicinal Chemistry, 2014, vol. 75, p. 184 - 194
[4] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 7, p. 1844 - 1848
O-ButylhydroxylaMine Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
O-ButylhydroxylaMine Hydrochloride Suppliers
- Tel
- 0371-56632527 13838252817
- Fax
- 0371-56635027
- sales@kingsfine.com
- Country
- China
- ProdList
- 98
- Advantage
- 62
- Tel
- 021-33690831-8001 13552411790
- Fax
- 021-33690831
- postmaster@tyjchem.cn
- Country
- China
- ProdList
- 1542
- Advantage
- 55
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
- Tel
- 021-65566949 13901795941
- Fax
- 86-21-51861665
- market@medpep.com
- Country
- China
- ProdList
- 156
- Advantage
- 66
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- +1(858) 699-3322
- Fax
- +1(858) 876-1948
- marketing@accelachem.com
- Country
- United States
- ProdList
- 6024
- Advantage
- 65
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9923
- Advantage
- 55
View Lastest Price from O-ButylhydroxylaMine Hydrochloride manufacturers
- Product
- O-ButylhydroxylaMine Hydrochloride 4490-82-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-06