S-1-CBZ-3-Hydroxy-piperidine
- Product Name
- S-1-CBZ-3-Hydroxy-piperidine
- CAS No.
- 94944-69-1
- Chemical Name
- S-1-CBZ-3-Hydroxy-piperidine
- Synonyms
- (S)-1-Cbz-3-hydroxy-piper...;S-1-CBZ-3-Hydroxy-piperidine;(S)-Benzyl 3-hydroxypiperidine-1-carboxylate;benzyl (3S)-3-hydroxypiperidine-1-carboxylate;Benzyl (3S)-3-hydroxy-1-piperidinecarboxylate;(3S)-3-Hydroxy-1-piperidinecarboxylic acid phenylmethyl ester;1-Piperidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester, (3S)-
- CBNumber
- CB52595547
- Molecular Formula
- C13H17NO3
- Formula Weight
- 235.28
- MOL File
- 94944-69-1.mol
S-1-CBZ-3-Hydroxy-piperidine Property
- Boiling point:
- 384.9±42.0 °C(Predicted)
- Density
- 1.220±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.72±0.20(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- AS55694-3S
- Product name
- (S)-1-Cbz-3-hydroxy-piperidine
- Purity
- 97+% ee
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- AS55694-3S
- Product name
- (S)-1-Cbz-3-hydroxy-piperidine
- Purity
- 97+% ee
- Packaging
- 5G
- Price
- $86
- Updated
- 2021/12/16
- Product number
- 9209AH
- Product name
- (S)-Benzyl3-hydroxypiperidine-1-carboxylate
- Packaging
- 5g
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 122482
- Product name
- (S)-1-Cbz-3-hydroxy-piperidine
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $166
- Updated
- 2021/12/16
- Product number
- 9209AH
- Product name
- (S)-Benzyl3-hydroxypiperidine-1-carboxylate
- Packaging
- 25g
- Price
- $211
- Updated
- 2021/12/16
S-1-CBZ-3-Hydroxy-piperidine Chemical Properties,Usage,Production
Synthesis
61995-20-8
94944-69-1
General procedure for the synthesis of benzyl (S)-3-hydroxypiperidine-1-carboxylate from 1-N-Cbz-3-piperidone: a reaction mixture of 1 mL of potassium phosphate buffer (100 mM, pH 7.0) containing 200 mM substrate (1-N-Cbz-3-piperidone), 1 mM NAD+, 5% (v/v) 2-propanol, and 10 mg of crude enzyme READH was incubated at 50°C warming. For ChKRED20, the reaction conditions were adjusted to contain 40% (v/v) 2-propanol and the reaction temperature was 40°C. The reaction progress was monitored by TLC and the reaction was extracted with methyl tert-butyl ether (1 mL) at the termination of the reaction. The organic phase was dried with anhydrous sodium sulfate and concentrated. The conversion and enantiomeric excess were determined by chiral HPLC. The products were purified by silica gel column chromatography and structurally characterized by NMR analysis, spinometry and mass spectrometry.
References
[1] Process Biochemistry, 2017, vol. 56, p. 90 - 97
S-1-CBZ-3-Hydroxy-piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from S-1-CBZ-3-Hydroxy-piperidine manufacturers
- Product
- S-1-CBZ-3-Hydroxy-piperidine 94944-69-1
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10
- Release date
- 2024-08-19
- Product
- Benzyl (3S)-3-hydroxy-1-piperidinecarboxylate 94944-69-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- Min98%HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-09