ChemicalBook > CAS DataBase List > S-1-CBZ-3-Hydroxy-piperidine

S-1-CBZ-3-Hydroxy-piperidine

Product Name
S-1-CBZ-3-Hydroxy-piperidine
CAS No.
94944-69-1
Chemical Name
S-1-CBZ-3-Hydroxy-piperidine
Synonyms
(S)-1-Cbz-3-hydroxy-piper...;S-1-CBZ-3-Hydroxy-piperidine;(S)-Benzyl 3-hydroxypiperidine-1-carboxylate;benzyl (3S)-3-hydroxypiperidine-1-carboxylate;Benzyl (3S)-3-hydroxy-1-piperidinecarboxylate;(3S)-3-Hydroxy-1-piperidinecarboxylic acid phenylmethyl ester;1-Piperidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester, (3S)-
CBNumber
CB52595547
Molecular Formula
C13H17NO3
Formula Weight
235.28
MOL File
94944-69-1.mol
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S-1-CBZ-3-Hydroxy-piperidine Property

Boiling point:
384.9±42.0 °C(Predicted)
Density 
1.220±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
14.72±0.20(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS55694-3S
Product name
(S)-1-Cbz-3-hydroxy-piperidine
Purity
97+% ee
Packaging
1g
Price
$32
Updated
2021/12/16
Activate Scientific
Product number
AS55694-3S
Product name
(S)-1-Cbz-3-hydroxy-piperidine
Purity
97+% ee
Packaging
5G
Price
$86
Updated
2021/12/16
AK Scientific
Product number
9209AH
Product name
(S)-Benzyl3-hydroxypiperidine-1-carboxylate
Packaging
5g
Price
$104
Updated
2021/12/16
Matrix Scientific
Product number
122482
Product name
(S)-1-Cbz-3-hydroxy-piperidine
Purity
97.0%
Packaging
1g
Price
$166
Updated
2021/12/16
AK Scientific
Product number
9209AH
Product name
(S)-Benzyl3-hydroxypiperidine-1-carboxylate
Packaging
25g
Price
$211
Updated
2021/12/16
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S-1-CBZ-3-Hydroxy-piperidine Chemical Properties,Usage,Production

Synthesis

61995-20-8

94944-69-1

General procedure for the synthesis of benzyl (S)-3-hydroxypiperidine-1-carboxylate from 1-N-Cbz-3-piperidone: a reaction mixture of 1 mL of potassium phosphate buffer (100 mM, pH 7.0) containing 200 mM substrate (1-N-Cbz-3-piperidone), 1 mM NAD+, 5% (v/v) 2-propanol, and 10 mg of crude enzyme READH was incubated at 50°C warming. For ChKRED20, the reaction conditions were adjusted to contain 40% (v/v) 2-propanol and the reaction temperature was 40°C. The reaction progress was monitored by TLC and the reaction was extracted with methyl tert-butyl ether (1 mL) at the termination of the reaction. The organic phase was dried with anhydrous sodium sulfate and concentrated. The conversion and enantiomeric excess were determined by chiral HPLC. The products were purified by silica gel column chromatography and structurally characterized by NMR analysis, spinometry and mass spectrometry.

References

[1] Process Biochemistry, 2017, vol. 56, p. 90 - 97

S-1-CBZ-3-Hydroxy-piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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S-1-CBZ-3-Hydroxy-piperidine Suppliers

Chembest Research Laboratories Limited
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sales@BioChemBest.com
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China
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Shanghai Jian Chao Chemical Technology Co., Ltd.
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Bide Pharmatech Ltd.
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Chengdu Firster Pharmaceutical Co., Ltd.
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028-87078428 028-87074958
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JW & Y Pharmlab Co., Ltd.
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SPIRO PHARMA
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Amadis Chemical Company Limited
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Sichuan mokai Technology Co., Ltd
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View Lastest Price from S-1-CBZ-3-Hydroxy-piperidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
S-1-CBZ-3-Hydroxy-piperidine 94944-69-1
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-08-19
Career Henan Chemical Co
Product
Benzyl (3S)-3-hydroxy-1-piperidinecarboxylate 94944-69-1
Price
US $1.00/g
Min. Order
1g
Purity
Min98%HPLC
Supply Ability
g/kg/ton
Release date
2020-01-09

94944-69-1, S-1-CBZ-3-Hydroxy-piperidineRelated Search:


  • benzyl (3S)-3-hydroxypiperidine-1-carboxylate
  • S-1-CBZ-3-Hydroxy-piperidine
  • (S)-1-Cbz-3-hydroxy-piper...
  • (S)-Benzyl 3-hydroxypiperidine-1-carboxylate
  • (3S)-3-Hydroxy-1-piperidinecarboxylic acid phenylmethyl ester
  • Benzyl (3S)-3-hydroxy-1-piperidinecarboxylate
  • 1-Piperidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester, (3S)-
  • 94944-69-1