3-(4-broMophenyl)piperidin-2-one
Uses Application- Product Name
- 3-(4-broMophenyl)piperidin-2-one
- CAS No.
- 769944-71-0
- Chemical Name
- 3-(4-broMophenyl)piperidin-2-one
- Synonyms
- 3-(4-broMophenyl)piperidin-2-one;3-(4-bromophenyl)-2-Piperidinone;2-Piperidinone, 3-(4-bromophenyl)-
- CBNumber
- CB52596610
- Molecular Formula
- C11H12BrNO
- Formula Weight
- 254.12
- MOL File
- 769944-71-0.mol
3-(4-broMophenyl)piperidin-2-one Property
- Boiling point:
- 416.4±45.0 °C(Predicted)
- Density
- 1.416±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 16.07±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Y6391
- Product name
- 3-(4-Bromophenyl)piperidin-2-one
- Packaging
- 250mg
- Price
- $296
- Updated
- 2021/12/16
- Product number
- Y6391
- Product name
- 3-(4-Bromophenyl)piperidin-2-one
- Packaging
- 1g
- Price
- $664
- Updated
- 2021/12/16
- Product number
- CM120334
- Product name
- 3-(4-Bromophenyl)-2-piperidinone
- Purity
- 95%
- Packaging
- 1g
- Price
- $426
- Updated
- 2021/12/16
- Product number
- CD11059623
- Product name
- 3-(4-Bromophenyl)piperidin-2-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $451
- Updated
- 2021/12/16
- Product number
- 769944710
- Product name
- 3-(4-Bromophenyl)piperidin-2-one
- Packaging
- 1g
- Price
- $464.1
- Updated
- 2021/12/16
3-(4-broMophenyl)piperidin-2-one Chemical Properties,Usage,Production
Uses
3-(4-bromophenyl)piperidin-2-one can be used as a pharmaceutical synthesis intermediate.
Application
3-(4-Bromophenyl)piperidin-2-one can be used as a pharmaceutical synthesis intermediate, such as in the preparation of:
The specific steps are as follows: Mix 3-(4-Bromophenyl)piperidin-2-one (7.6g, 30mmol) in... In deuterated methanol (100 g), under nitrogen protection, the mixture was heated to 40–45 °C, and sodium methoxide (3.2 g, 60 mmol) was added. The reaction was continued at 40–45 °C for 16 h. LC-MS analysis showed a deuteration rate of 90%. The reaction solution was cooled to 20–25 °C, quenched with 100 mL of ammonium chloride solution, extracted with ethyl acetate (100 mL × 2), dried, concentrated to obtain a crude product, and filtered with petroleum ether to obtain 7.0 g of a white solid, 3-(4-bromophenyl)-3-deuterated piperidin-2-one, with a yield of 92%. LC-MS analysis showed a deuteration rate of 92%, and NMR analysis showed a deuteration rate of 94%.
3-(4-broMophenyl)piperidin-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-broMophenyl)piperidin-2-one Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69