2,5-DibroMopyridine-3,4-diaMine
- Product Name
- 2,5-DibroMopyridine-3,4-diaMine
- CAS No.
- 221241-11-8
- Chemical Name
- 2,5-DibroMopyridine-3,4-diaMine
- Synonyms
- 2,5-dibroM-3,4-diaMinopyridin;2,5-dibromo-3,4-diaminopyridine;2,5-Dibromo-3,4-pyridinediamine;3,4-DiaMino-2,5-dibroMopyridine;2,5-DibroMopyridine-3,4-diaMine;3,4-PyridinediaMine, 2,5-dibroMo-
- CBNumber
- CB52605978
- Molecular Formula
- C5H5Br2N3
- Formula Weight
- 266.92
- MOL File
- 221241-11-8.mol
2,5-DibroMopyridine-3,4-diaMine Property
- Melting point:
- 217-218℃ (methanol )
- Boiling point:
- 395.7±37.0 °C(Predicted)
- Density
- 2.232±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 2.84±0.50(Predicted)
- Appearance
- Light yellow to brown Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D416633
- Product name
- 3,4-Diamino-2,5-dibromopyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3H30-9-12
- Product name
- 2,5-Dibromopyridine-3,4-diamine
- Packaging
- 1g
- Price
- $103
- Updated
- 2021/12/16
- Product number
- 097146
- Product name
- 2,5-Dibromopyridine-3,4-diamine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $394
- Updated
- 2021/12/16
- Product number
- HCH0362841
- Product name
- 2,5-DIBROMOPYRIDINE-3,4-DIAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.15
- Updated
- 2021/12/16
- Product number
- 097146
- Product name
- 2,5-Dibromopyridine-3,4-diamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $874
- Updated
- 2021/12/16
2,5-DibroMopyridine-3,4-diaMine Chemical Properties,Usage,Production
Synthesis
54-96-6
221241-11-8
The synthesis of 3,4-diamino-2,5-dibromopyridine was improved based on the method reported in literature [18]. The procedure was as follows: in a 250 mL three-necked round-bottomed flask equipped with a magnetic stirrer, pyridine-3,4-diamine (2 g, 18.3 mmol) was mixed with 48% aqueous hydrobromic acid (30 mL). After heating the mixture to 100 °C, bromine (2.5 mL) was added slowly and the reaction solution was subsequently stirred at 135 °C for 5 hours. After completion of the reaction, the mixture was cooled to room temperature and a yellow precipitate was obtained by adding aqueous sodium thiosulfate solution, aqueous sodium carbonate solution and distilled water sequentially. The precipitate was separated by filtration and washed three times with distilled water. Finally, recrystallization was carried out using a solvent mixture of toluene and tetrahydrofuran (5:1, v/v) to give a white flocculent solid in 50% yield. The structure of the product was confirmed by 1H NMR (DMSO, 400 MHz, ppm) and 13C NMR (DMSO, 101 MHz, ppm): 1H NMR δ = 7.53 (s, 1H), 5.99 (s, 2H), 5.03 (s, 2H); 13C NMR δ = 139.93, 139.13, 129.54, 126.67 , 106.22 (see Figure S1 in the Supporting Information for details).
References
[1] Patent: US2014/94456, 2014, A1. Location in patent: Paragraph 0612-0613; 0635-0636
[2] Patent: WO2015/153683, 2015, A1. Location in patent: Paragraph 0360
[3] Chemistry of Materials, 2016, vol. 28, # 7, p. 2058 - 2066
[4] Journal of Polymer Science, Part A: Polymer Chemistry, 2016, vol. 54, # 12, p. 1822 - 1833
[5] RSC Advances, 2014, vol. 4, # 106, p. 61537 - 61547
2,5-DibroMopyridine-3,4-diaMine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,5-DibroMopyridine-3,4-diaMine manufacturers
- Product
- 2,5-DibroMopyridine-3,4-diaMine 221241-11-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-08