1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-

Product Name
1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
CAS No.
478082-99-4
Chemical Name
1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
Synonyms
Ro4368554;7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole;3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole;1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
CBNumber
CB52606566
Molecular Formula
C19H21N3O2S
Formula Weight
355.45
MOL File
478082-99-4.mol
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1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Property

Melting point:
160-162 °C
Boiling point:
596.8±50.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: >10mg/mL
form 
powder
pka
15.49±0.30(Predicted)
color 
off-white
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R8782
Product name
Ro4368554
Purity
≥98% (HPLC)
Packaging
5mg
Price
$197
Updated
2022/05/15
Sigma-Aldrich
Product number
R8782
Product name
Ro4368554
Purity
≥98% (HPLC)
Packaging
25mg
Price
$759
Updated
2022/05/15
Usbiological
Product number
464796
Product name
Ro4368554
Packaging
5mg
Price
$403
Updated
2021/12/16
TRC
Product number
R700880
Product name
Ro4368554
Packaging
10mg
Price
$185
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008409
Product name
RO4368554
Purity
95.00%
Packaging
10MG
Price
$619.72
Updated
2021/12/16
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1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Chemical Properties,Usage,Production

Uses

Ro4368554 is a selective 5-Hydroxytryptamine 6 (5-HT6) receptor antagonists.

Biochem/physiol Actions

Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Suppliers

478082-99-4, 1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-Related Search:


  • 1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
  • 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole
  • 7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole
  • Ro4368554
  • 478082-99-4