3-Hydroxy-3-methylpyrrolidine hydrochloride
- Product Name
- 3-Hydroxy-3-methylpyrrolidine hydrochloride
- CAS No.
- 921592-91-8
- Chemical Name
- 3-Hydroxy-3-methylpyrrolidine hydrochloride
- Synonyms
- 3-Methyl-3-pyrrolidinol HCl;3-HYDROXY-3-METHYLPYRROLIDINE HCL;3-Methyl-3-Pyrrolidinol hydrochloride;3-methylpyrrolidin-3-ol hydrochloride;3-Hydroxy-3-methylpyrrolidine hydrochloride
- CBNumber
- CB52613634
- Molecular Formula
- C5H12ClNO
- Formula Weight
- 137.61
- MOL File
- 921592-91-8.mol
3-Hydroxy-3-methylpyrrolidine hydrochloride Property
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Orange to Very Dark Brown
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M320950
- Product name
- 3-Methylpyrrolidin-3-olHydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- AK100495
- Product name
- 3-Methylpyrrolidin-3-olhydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $81
- Updated
- 2021/12/16
- Product number
- 4H56-5-0D
- Product name
- 3-Hydroxy-3-methylpyrrolidine hydrochloride
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 068619
- Product name
- 3-Hydroxy-3-methylpyrrolidine hydrochloride
- Purity
- >95%
- Packaging
- 250mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- AK100495
- Product name
- 3-Methylpyrrolidin-3-olhydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $284
- Updated
- 2021/12/16
3-Hydroxy-3-methylpyrrolidine hydrochloride Chemical Properties,Usage,Production
Uses
3-Methylpyrrolidin-3-ol Hydrochloride can be used to treat inflammatory disorders.
Synthesis
412278-02-5
921592-91-8
The general procedure for the synthesis of 3-hydroxy-3-methylpyrrolidine-1-carboxylic acid tert-butyl ester from 3-hydroxy-3-methylpyrrolidine-1-carboxylic acid is as follows: tert-butyl 3-hydroxy-3-methylpyrrolidine-1-carboxylic acid tert-butyl ester (0.027 g, 0.13 mmol) was added to a solution of 4N HCl/dioxane (1 ml), and the reaction mixture was stirred for 2 hours at room temperature. After completion of the reaction, the solution was concentrated under reduced pressure to remove the solvent. The concentrated residue was diluted with toluene (1 ml) and concentrated again under reduced pressure to finally obtain 3-hydroxy-3-methylpyrrolidine hydrochloride as a colorless oil (0.018 g, 100% yield).
References
[1] Patent: WO2008/24725, 2008, A1. Location in patent: Page/Page column 124
[2] Patent: EP2703398, 2014, A1. Location in patent: Paragraph 0121; 0122
[3] Patent: EP2703398, 2014, A1. Location in patent: Paragraph 0175; 0176
[4] Patent: WO2016/100940, 2016, A1. Location in patent: Page/Page column 156
[5] Patent: WO2007/11284, 2007, A1. Location in patent: Page/Page column 29
3-Hydroxy-3-methylpyrrolidine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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