2-chloro-3-nitro-6-phenylpyridine
- Product Name
- 2-chloro-3-nitro-6-phenylpyridine
- CAS No.
- 187242-88-2
- Chemical Name
- 2-chloro-3-nitro-6-phenylpyridine
- Synonyms
- EOS-60527;2-chloro-3-nitro-6-phenylpyridine;Pyridine, 2-chloro-3-nitro-6-phenyl-
- CBNumber
- CB52616246
- Molecular Formula
- C11H7ClN2O2
- Formula Weight
- 234.64
- MOL File
- 187242-88-2.mol
2-chloro-3-nitro-6-phenylpyridine Property
- Boiling point:
- 376.1±37.0 °C(Predicted)
- Density
- 1.366±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -4.20±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C11H7ClN2O2/c12-11-10(14(15)16)7-6-9(13-11)8-4-2-1-3-5-8/h1-7H
- InChIKey
- FEXPVVIOGUUGJM-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(C2=CC=CC=C2)=CC=C1[N+]([O-])=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC153688
- Product name
- 2-chloro-3-nitro-6-phenylpyridine
- Packaging
- 250mg
- Price
- $67.5
- Updated
- 2021/12/16
- Product number
- FC153688
- Product name
- 2-chloro-3-nitro-6-phenylpyridine
- Packaging
- 500mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 9768AF
- Product name
- 2-Chloro-3-nitro-6-phenylpyridine
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FC153688
- Product name
- 2-chloro-3-nitro-6-phenylpyridine
- Packaging
- 1g
- Price
- $201.25
- Updated
- 2021/12/16
- Product number
- 9768AF
- Product name
- 2-Chloro-3-nitro-6-phenylpyridine
- Packaging
- 5g
- Price
- $290
- Updated
- 2021/12/16
2-chloro-3-nitro-6-phenylpyridine Chemical Properties,Usage,Production
Synthesis
16013-85-7
98-80-6
187242-88-2
Preparation of 2-chloro-3-nitro-6-phenylpyridine: To an anhydrous 1,4-dioxane solution of 2,6-dichloro-3-nitropyridine (1.00 g, 5.18 mmol) was added phenylboronic acid (0.695 g, 5.70 mmol), cesium carbonate (2 M aqueous solution, 7.5 mL, 15 mmol) and tetrakis(triphenylphosphine)palladium (0.025 g, 0.02 mmol). The reaction mixture was displaced three times with nitrogen and heated in a microwave reactor at 100 °C for 10 min. After completion of the reaction, it was cooled to room temperature and the reaction solution was poured into water and extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: 5% ethyl acetate/hexane) to afford the target compound 2-chloro-3-nitro-6-phenylpyridine (0.5 g, 41% yield). LC-MS (m/z): 235 [M+H]+.
References
[1] Patent: US2008/242685, 2008, A1. Location in patent: Page/Page column 16
2-chloro-3-nitro-6-phenylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-chloro-3-nitro-6-phenylpyridine Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 2-chloro-3-nitro-6-phenylpyridine manufacturers
- Product
- 2-chloro-3-nitro-6-phenylpyridine 187242-88-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2-chloro-3-nitro-6-phenylpyridine 187242-88-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09