1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE
- Product Name
- 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE
- CAS No.
- 1126367-34-7
- Chemical Name
- 1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE
- Synonyms
- 2-Nitro-4-Bromo-5-Chlorotoluene;4-Bromo-5-chloro-2-nitrotoluene;1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE;Benzene, 1-broMo-2-chloro-4-Methyl-5-nitro-
- CBNumber
- CB5261765
- Molecular Formula
- C7H5BrClNO2
- Formula Weight
- 250.48
- MOL File
- Mol file
1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE Property
- Boiling point:
- 303.6±37.0 °C(Predicted)
- Density
- 1.719±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B789360
- Product name
- 1-Bromo-2-chloro-4-methyl-5-nitrobenzene
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- 2200AA
- Product name
- 1-Bromo-2-chloro-4-methyl-5-nitrobenzene
- Packaging
- 1g
- Price
- $101
- Updated
- 2021/12/16
- Product number
- 4754-D-00
- Product name
- 1-Bromo-2-chloro-4-methyl-5-nitrobenzene
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 4754-D-00
- Product name
- 1-Bromo-2-chloro-4-methyl-5-nitrobenzene
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $290
- Updated
- 2021/12/16
- Product number
- 2200AA
- Product name
- 1-Bromo-2-chloro-4-methyl-5-nitrobenzene
- Packaging
- 5g
- Price
- $223
- Updated
- 2021/12/16
1-BROMO-2-CHLORO-4-METHYL-5-NITRO-BENZENE Chemical Properties,Usage,Production
Synthesis
6627-51-6
1126367-34-7
General procedure for the synthesis of 1-bromo-2-chloro-4-methyl-5-nitrobenzene from 3-chloro-4-bromotoluene: Concentrated nitric acid (15 mL) was added slowly and dropwise to a solution of 1-bromo-2-chloro-4-methylbenzene (20 g, 100 mmol) in concentrated sulfuric acid (65 mL) at -20°C. The reaction was quenched by stirring for 5 minutes. The reaction mixture was stirred for 5 minutes and then poured into ice water (500 g) to quench the reaction. Subsequently, the mixture was filtered, the solid product was washed with water and dried to give the crude product as a yellow solid (23 g, 95% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.27 (s, 1H), 7.46 (s, 1H), 2.56 (s, 3H).
References
[1] Patent: WO2017/12576, 2017, A1. Location in patent: Page/Page column 332
[2] Patent: WO2009/27746, 2009, A1. Location in patent: Page/Page column 80
[3] Patent: WO2018/137593, 2018, A1. Location in patent: Page/Page column 83