Methyl 2-Methyl-3-(trifluoroMethyl)benzoate
- Product Name
- Methyl 2-Methyl-3-(trifluoroMethyl)benzoate
- CAS No.
- 346603-63-2
- Chemical Name
- Methyl 2-Methyl-3-(trifluoroMethyl)benzoate
- Synonyms
- Methyl 2-Methyl-3-(trifluoroMethyl)benzoate;2-Methyl-3-(trifluoromethyl)benzoic acid methyl ester;Benzoic acid, 2-methyl-3-(trifluoromethyl)-, methyl ester
- CBNumber
- CB52620010
- Molecular Formula
- C10H9F3O2
- Formula Weight
- 218.17
- MOL File
- 346603-63-2.mol
Methyl 2-Methyl-3-(trifluoroMethyl)benzoate Property
- Boiling point:
- 220℃
- Density
- 1.231
- Flash point:
- 68℃
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C10H9F3O2/c1-6-7(9(14)15-2)4-3-5-8(6)10(11,12)13/h3-5H,1-2H3
- InChIKey
- KFJGSNVBDYRBAD-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=CC=CC(C(F)(F)F)=C1C
Safety
- HS Code
- 9999999999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- V5351
- Product name
- Methyl2-methyl-3-(trifluoromethyl)benzoate
- Packaging
- 1g
- Price
- $156
- Updated
- 2021/12/16
- Product number
- V5351
- Product name
- Methyl2-methyl-3-(trifluoromethyl)benzoate
- Packaging
- 5g
- Price
- $371
- Updated
- 2021/12/16
- Product number
- HCH0369218
- Product name
- METHYL-2-METHYL-3-(TRIFLUOROMETHYL)BENZOATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.2
- Updated
- 2021/12/16
- Product number
- V5351
- Product name
- Methyl2-methyl-3-(trifluoromethyl)benzoate
- Packaging
- 25g
- Price
- $1051
- Updated
- 2021/12/16
- Product number
- A351996
- Product name
- Methyl2-methyl-3-(trifluoromethyl)benzoate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
Methyl 2-Methyl-3-(trifluoroMethyl)benzoate Chemical Properties,Usage,Production
Synthesis
67-56-1
62089-35-4
346603-63-2
1. 2-Methyl-3-(trifluoromethyl)benzoic acid (30 g, 147 mmol) was added to a 500 mL round-bottomed flask equipped with an air condenser and a stirrer. 2. the solid was dissolved in methanol (101 mL), followed by the slow addition of sulfuric acid (8.22 mL, 154 mmol). 3. a condenser was assembled and the reaction mixture was heated to 75 °C and kept at this temperature for the reaction overnight. 4. Upon completion of the reaction, the mixture was cooled to room temperature and neutralized by the slow addition of 1N NaOH solution (~155 mL). 5. The reaction mixture was extracted with ether (3 x 300 mL), the organic layers were combined and dried over anhydrous magnesium sulfate. 6. The organic layer was concentrated under pressure to give an oil, which was further cured under vacuum to give methyl 2-methyl-3-(trifluoromethyl)benzoate as a white solid (28.25 g, 129 mmol, 88% yield). 7. The product was analyzed by 1H NMR. 7. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 2.54 (d, J = 1.78 Hz, 3H), 3.89 (s, 3H), 7.53 (t, J = 7.83 Hz, 1H), 7.89 (d, J = 7.83 Hz, 1H), 7.97 (d, J = 7.83 Hz, 1H).
References
[1] Patent: US2012/283271, 2012, A1. Location in patent: Page/Page column 10
[2] Patent: WO2010/135504, 2010, A1. Location in patent: Page/Page column 101
Methyl 2-Methyl-3-(trifluoroMethyl)benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2-Methyl-3-(trifluoroMethyl)benzoate manufacturers
- Product
- Methyl 2-Methyl-3-(trifluoroMethyl)benzoate 346603-63-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16
- Product
- Methyl 2-Methyl-3-(trifluoroMethyl)benzoate 346603-63-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16