ChemicalBook > CAS DataBase List > 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL

2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL

Product Name
2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL
CAS No.
56456-51-0
Chemical Name
2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL
Synonyms
2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL;2-CHLORO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL;2-Chloro-4-(trifluoromethyl)benzenemethanol;2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL]METHANOL;2-Chloro-4-(trifluoromethyl)benzylalcohol,97%;BENZENEMETHANOL, 2-CHLORO-4-(TRIFLUOROMETHYL)-
CBNumber
CB5262065
Molecular Formula
C8H6ClF3O
Formula Weight
210.58
MOL File
56456-51-0.mol
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2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL Property

Melting point:
50-52℃
Boiling point:
227℃
Density 
1.416
Flash point:
91℃
storage temp. 
Sealed in dry,Room Temperature
pka
13.66±0.10(Predicted)
Appearance
Off-white to light yellow Solid
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36
HS Code 
2909498090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
C432945
Product name
2-Chloro-4-(trifluoromethyl)benzylalcohol
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
C432945
Product name
2-Chloro-4-(trifluoromethyl)benzylalcohol
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
074302
Product name
2-Chloro-4-(trifluoromethyl)benzylalcohol
Purity
95+%
Packaging
1g
Price
$28
Updated
2021/12/16
Matrix Scientific
Product number
074302
Product name
2-Chloro-4-(trifluoromethyl)benzylalcohol
Purity
95+%
Packaging
5g
Price
$84
Updated
2021/12/16
Matrix Scientific
Product number
074302
Product name
2-Chloro-4-(trifluoromethyl)benzylalcohol
Purity
95+%
Packaging
10g
Price
$143
Updated
2021/12/16
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2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL Chemical Properties,Usage,Production

Uses

2-Chloro-4-(trifluoromethyl)benzylalcohol

Synthesis

23228-45-7

56456-51-0

The general procedure for the synthesis of 2-chloro-4-trifluoromethylbenzyl alcohol from 2-chloro-4-trifluoromethylbenzoic acid was as follows: 2-chloro-4-trifluoromethylbenzoic acid (2.50 g) was added to a tetrahydrofuran solution (30 mL) containing sodium borohydride, and the reaction was stirred for 1 h at room temperature. Upon completion of the reaction, the reaction mixture was slowly poured into 1N hydrochloric acid solution and extracted with ethyl acetate. The organic phases were combined, washed sequentially with aqueous sodium bicarbonate and saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent. The crude product obtained was purified by silica gel column chromatography with gradient elution using ethyl acetate-hexane (1:24 to 1:4, v/v) as eluent, and the target components were collected and concentrated under reduced pressure to obtain 2-chloro-4-trifluoromethylbenzenemethanol (2.23 g, yield: 96%), which was a colorless oil. Its 1H-NMR (300 MHz, CDCl3) data were as follows: δ 4.85 (2H, d, J = 9.0 Hz), 7.52-7.80 (3H, m).

References

[1] Patent: WO2007/18314, 2007, A2. Location in patent: Page/Page column 165-166
[2] Patent: EP1829863, 2007, A1
[3] Patent: WO2006/57448, 2006, A1. Location in patent: Page/Page column 163

2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL Suppliers

Alchem Pharmtech,Inc.
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United States
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Aladdin Scientific
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Matrix Scientific
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AcceleDev Chemical LLC
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View Lastest Price from 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL manufacturers

Career Henan Chemical Co
Product
2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL 56456-51-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

56456-51-0, 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOLRelated Search:


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  • 2-Chloro-4-(trifluoromethyl)benzenemethanol
  • 2-CHLORO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL
  • 2-CHLOR-4-TRIFLUOROMETHYL-BENZYLALCOHOL
  • BENZENEMETHANOL, 2-CHLORO-4-(TRIFLUOROMETHYL)-
  • 2-Chloro-4-(trifluoromethyl)benzylalcohol,97%
  • 56456-51-0
  • 56546-51-0
  • Fluorine series