4-BroMopyridazine HydrobroMide
- Product Name
- 4-BroMopyridazine HydrobroMide
- CAS No.
- 1220039-64-4
- Chemical Name
- 4-BroMopyridazine HydrobroMide
- Synonyms
- 4-BroMopyridazine HydrobroMide;5-Bromopyridazine hydrobromide;Pyridazine, 4-bromo-, hydrobromide (1:1)
- CBNumber
- CB52621491
- Molecular Formula
- C4H4Br2N2
- Formula Weight
- 239.89596
- MOL File
- 1220039-64-4.mol
4-BroMopyridazine HydrobroMide Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightky)
- form
- Solid
- color
- Green to Dark Grey
- Stability:
- Shock sensitive, temperature sensitive, light sensitive
- InChI
- InChI=1S/C4H3BrN2.BrH/c5-4-1-2-6-7-3-4;/h1-3H;1H
- InChIKey
- KSJDIQGRNABAMU-UHFFFAOYSA-N
- SMILES
- C1=NN=CC=C1Br.[H]Br
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B686785
- Product name
- 4-BromopyridazineHydrobromide
- Packaging
- 1g
- Price
- $1135
- Updated
- 2021/12/16
- Product number
- OR49036
- Product name
- 4-Bromopyridazinehydrobromide
- Purity
- 95%
- Packaging
- 5g
- Price
- $762
- Updated
- 2021/12/16
- Product number
- 3H32-9-BT
- Product name
- 4-Bromopyridazinehydrobromide
- Purity
- 95%
- Packaging
- 5G
- Price
- $840
- Updated
- 2021/12/16
- Product number
- Z1972
- Product name
- 4-Bromopyridazinehydrobromide
- Packaging
- 1g
- Price
- $849
- Updated
- 2021/12/16
- Product number
- OR49036
- Product name
- 4-Bromopyridazinehydrobromide
- Purity
- 95%
- Packaging
- 250mg
- Price
- $87
- Updated
- 2021/12/16
4-BroMopyridazine HydrobroMide Chemical Properties,Usage,Production
Uses
4-Bromopyridazine Hydrobromide is a mono-substituted pyridazine derivative used in the preparation of γ-secretase modulators.
Uses
As a mono-substituted pyridazine derivative, 4-Bromo-pyridazine hydrobromide can be used in the preparation of γ-secretase modulators.
Synthesis
4-Bromopyridazine is synthesized from 3,6-dichloropyridazine in four steps. 1) 3,6-Dichloropyridazine reacts with chlorine at 100C to give 3,4,6-trichloropyridazine. 2) 3,4,6-Trichloropyridazine is refluxed with 15% NaOH solution. After acidification and recrystallization, 3,6-dichloro-4-hydroxypyridazine is obtained. 3) 3,6-Dichloro-4-hydroxypyridazine is subjected to pressurized hydrogenation in methanol in an autoclave using Pd/C as catalyst. Work-up yields 4-hydroxypyridazine. 4) 4-Hydroxypyridazine reacts with phosphorus tribromide oxide. After pH adjustment with ammonia, chloroform extraction, column chromatography, and recrystallization, 4-bromopyridazine is obtained.
4-BroMopyridazine HydrobroMide Preparation Products And Raw materials
Raw materials
Preparation Products
4-BroMopyridazine HydrobroMide Suppliers
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View Lastest Price from 4-BroMopyridazine HydrobroMide manufacturers
- Product
- 4-BroMopyridazine HydrobroMide 1220039-64-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-02-18