ChemicalBook > CAS DataBase List > (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide

(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide

Product Name
(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide
CAS No.
1296129-15-1
Chemical Name
(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide
Synonyms
Ezetimibe-3;EZT cyclic ether;Ezetimibe Impuriry C;Ezetimibe Tetrahydropyran;Impurity C of ezetimium cloth;Ezetimibe Impurity 17(SCH59566);EzetiMibe Tetrahydropyran IMpurity;(2R,3R,6S)-N,6-bis(4-fluorophenyl);Ezetimibe tetrahydropyran Impurity 56;Ezetimibe Tetrahydropyran Analog(USP)
CBNumber
CB52622665
Molecular Formula
C24H21F2NO3
Formula Weight
409.43
MOL File
1296129-15-1.mol
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(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide Property

Melting point:
237-239°C
Boiling point:
626.7±55.0 °C(Predicted)
Density 
1.315±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.89±0.30(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
E975080
Product name
EzetimibeTetrahydropyranImpurity
Packaging
5mg
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
40416
Product name
EzetimibeTetrahydropyranImpurity
Packaging
5mg
Price
$650
Updated
2021/12/16
Crysdot
Product number
CD11298547
Product name
(2R,3R,6S)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide
Purity
97%
Packaging
1g
Price
$887
Updated
2021/12/16
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(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide Chemical Properties,Usage,Production

Uses

Ezetimibe (E975000) tetrahydropyran impurity.

(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide Suppliers

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1296129-15-1, (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMideRelated Search:

(3S,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one ent-EzetiMibe (αR,δS)-4-Fluoro-N-(4-fluorophenyl)-δ-hydroxy-α-[(4-hydroxyphenyl)Methyl]benzenepentanaMide (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One 3-O-Acetyl Ezetimibe Ezetimibe Impurity 70 4-p-toluoylbutyricacid 5-(4-FLUOROPHENYL)VALERIC ACID Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate Ezetimibe Benzyl Impurity (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one EzetiMibe Azetidinone Ring-opened IMpurity (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid (S)-(+)-4-Phenyl-2-oxazolidinone 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone

  • EzetiMibe Tetrahydropyran IMpurity
  • (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide
  • EzetiMibe Tetrahydropyran IMpurity (SCH59566)
  • Ezetimibe Impurity 17(SCH59566)
  • (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxaMide
  • EZT cyclic ether
  • Ezetimibe Tetrahydropyran Impurity/(2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide
  • (2R,3R,6S)-N,6-bis(4-fluorophenyl)
  • Ezetimibe-3
  • Ezetimibe impuriry 1/Ezetimibe Tetrahydropyran Impurity/(2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide
  • (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)oxane-3-carboxamide
  • Ezetimibe Impurity 56 (Tetrahydropyran Impurity)
  • 2H-Pyran-3-carboxamide, N,6-bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-, (2R,3R,6S)-
  • Impurity C of ezetimium cloth
  • Ezetimibe Impurity 36(Tetrahydropyran Impurity)
  • Ezetimibe Impuriry C
  • (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide? (Ezetimibe Impurity）
  • Ezetimibe Tetrahydropyran
  • Ezetimibe Impurity 56 (Tetrahydropyran Impurity) (SCH59566)
  • Ezetimibe tetrahydropyran Impurity 56
  • Ezetimibe Tetrahydropyran Analog(USP)
  • (2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide - [B89049]
  • 1296129-15-1
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