ChemicalBook > CAS DataBase List > Calcitetrol

Calcitetrol

Product Name: Calcitetrol
CAS No.: 72203-93-1
Chemical Name: Calcitetrol
Synonyms: Calcitetrol;25-Trihydroxy VD3;1α, 24, 25-Trihydroxy VD3;1alpha,24,25-Trihydroxyvitamin D3;Calcitetrol(1α, 24, 25-Trihydroxy VD3);(1R,3S,5Z)-5-[(2E)-2-[1-[(1R)-4,5-Dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol;1,3-Cyclohexanediol, 5-[(2E)-2-[1-[(1R)-4,5-dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-
CBNumber: CB52624104
Molecular Formula: C27H44O4
Formula Weight: 432.64
MOL File: 72203-93-1.mol

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Calcitetrol Property

Boiling point:: 607.8±55.0 °C(Predicted)
Density: 1.10
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 14.43±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0808
Product name: Calcitetrol
Purity: 97.98%
Packaging: 1mg
Price: $420
Updated: 2021/12/16

Crysdot

Product number: CD31000975
Product name: Calcitetrol
Purity: 98+%
Packaging: 5mg
Price: $840
Updated: 2021/12/16

CSNpharm

Product number: CSN18404
Product name: Calcitetrol
Packaging: 5mg
Price: $1152
Updated: 2021/12/16

CSNpharm

Product number: CSN18404
Product name: Calcitetrol
Packaging: 1mg
Price: $336
Updated: 2021/12/16

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Calcitetrol Chemical Properties,Usage,Production

Uses

Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups. IC50 value: Target: Calcitriol increases blood calcium levels ([Ca2+]) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine. Calcitriol also stimulates release of calcium from bone by its action on the specific type of bone cells referred to as osteoblasts, causing them to release RANKL, which in turn activates osteoclasts.

References

[1] Akiyoshi-Shibata M, et al. Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli. Eur J Biochem. 1994 Sep 1;224(2):335-43. DOI:10.1111/j.1432-1033.1994.00335.x

Calcitetrol Preparation Products And Raw materials

Raw materials

Preparation Products

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72203-93-1, CalcitetrolRelated Search:

PURPURIN

Calcitetrol

(1R,3S,5Z)-5-[(2E)-2-[1-[(1R)-4,5-Dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol

1alpha,24,25-Trihydroxyvitamin D3

Calcitetrol(1α, 24, 25-Trihydroxy VD3)

25-Trihydroxy VD3

1α, 24, 25-Trihydroxy VD3

1,3-Cyclohexanediol, 5-[(2E)-2-[1-[(1R)-4,5-dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-

72203-93-1