ChemicalBook > CAS DataBase List > 4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline

Product Name
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
CAS No.
630125-91-6
Chemical Name
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
Synonyms
4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline;4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline;Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
CBNumber
CB52627024
Molecular Formula
C14H20F3N3
Formula Weight
287.32
MOL File
630125-91-6.mol
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4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Property

Boiling point:
344.9±42.0 °C(Predicted)
Density 
1.195±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
soluble in Dichloromethane;
form 
Solid
pka
7.76±0.10(Predicted)
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E924295
Product name
4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine
Packaging
50mg
Price
$430
Updated
2021/12/16
TRC
Product number
E924295
Product name
4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine
Packaging
250mg
Price
$1850
Updated
2021/12/16
ChemScene
Product number
CS-M1925
Product name
4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
Purity
99.10%
Packaging
1g
Price
$303
Updated
2021/12/16
ChemScene
Product number
CS-M1925
Product name
4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
Purity
99.10%
Packaging
10g
Price
$1519
Updated
2021/12/16
Matrix Scientific
Product number
183114
Product name
4-(4-Ethylpiperazin-1-ylmethyl)-3-trifluoromethylphenylamine
Purity
95%
Packaging
2.500g
Price
$1568
Updated
2021/12/16
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4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Chemical Properties,Usage,Production

Uses

4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N''-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline Suppliers

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630125-91-6, 4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)anilineRelated Search:


  • 4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
  • 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline
  • Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
  • 630125-91-6
  • 3630125-91-6