ChemicalBook > CAS DataBase List > BAY 869766
BAY 869766
- Product Name
- BAY 869766
- CAS No.
- 923032-38-6
- Chemical Name
- BAY 869766
- Synonyms
- RDEA119 R enantiomer;Thiocoraline Impurity2;BAY 869766 R enantiomer;RefaMetinib (R enantioMer);RefaMetinib (RDEA-119, BAY 86-9766);Refametinib (BAY 869766) R enantiomer;RDEA119; RDEA 119; BAY 86-9766; BAY 869766; BAY869766;RDEA119 R enantiomer|||Refametinib R enantiomer|||BAY 869766 R enantiomer;N-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-[(2R)-2,3-dihydroxypropyl]cyclopropanesulfonamide;Cyclopropanesulfonamide, N-[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl]-1-[(2R)-2,3-dihydroxypropyl]-
- CBNumber
- CB52627367
- Molecular Formula
- C19H20F3IN2O5S
- Formula Weight
- 572.34
- MOL File
- 923032-38-6.mol
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BAY 869766 Property
- Boiling point:
- 566.9±60.0 °C(Predicted)
- Density
- 1.82±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 15.54±0.20(Predicted)
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Safety
- HS Code
- 2933998090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-1687
- Product name
- RefametinibRenantiomer
- Packaging
- 5mg
- Price
- $220
- Updated
- 2021/12/16
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BAY 869766 Chemical Properties,Usage,Production
Uses
Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM.
IC 50
MEK: 2-15 nM (EC50)
References
[1] Andreas Maderna, et al. N-(arylamino)-sulfonamide inhibitors of mek. WO 2007014011 A2.
BAY 869766 Preparation Products And Raw materials
Raw materials
Preparation Products
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