11BETA-PGF2ALPHA-EA
- Product Name
- 11BETA-PGF2ALPHA-EA
- CAS No.
- 714966-38-8
- Chemical Name
- 11BETA-PGF2ALPHA-EA
- Synonyms
- 11BETA-PGF2ALPHA-EA;11β-Prostaglandin F2α Ethanolamide;11BETA-PROSTAGLANDIN F2ALPHA ETHANOLAMIDE;N-(2-HYDROXYETHYL)-9ALPHA, 11BETA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE;Prosta-5,13-dien-1-amide, 9,11,15-trihydroxy-N-(2-hydroxyethyl)-, (5Z,9α,11β,13E,15S)-;(Z)-7-[(1R,2R,3S,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide
- CBNumber
- CB5263800
- Molecular Formula
- C22H39NO5
- Formula Weight
- 397.55
- MOL File
- 714966-38-8.mol
11BETA-PGF2ALPHA-EA Property
- solubility
- DMF: Miscible; DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16522
- Product name
- 11β-Prostaglandin F2α Ethanolamide
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 16522
- Product name
- 11β-Prostaglandin F2α Ethanolamide
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $459
- Updated
- 2024/03/01
- Product number
- 16522
- Product name
- 11β-Prostaglandin F2α Ethanolamide
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $712
- Updated
- 2021/12/16
- Product number
- 1143AH
- Product name
- 11beta-PGF2alpha-EA
- Packaging
- 10mg
- Price
- $1061
- Updated
- 2021/12/16
11BETA-PGF2ALPHA-EA Chemical Properties,Usage,Production
Description
11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs.2,3 PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.3
Uses
11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
Definition
ChEBI: 11beta-prostaglandin F2alpha ethanolamide is an N-acylethanolamine resulting from the formal condensation of the carboxy group 11-epi-prostaglandin F2alpha with the amino group of ethanolamine. It is a N-acylethanolamine and a monocarboxylic acid amide. It is functionally related to an 11-epi-prostaglandin F2alpha.
References
1. Bachur, N.R., Masek, K., Melmon, K.L., et al. Fatty acid amides of ethanolamine in mammalian tissues J. Biol. Chem. 240,1019-1024(1965).
2. Yu, M., Ives, D., and Ramesha, C.S. Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-
3. Kozak, K.R., Crews, B.C., Morrow, J.D., et al. Metabolism of the endocannabinoids, 2-
11BETA-PGF2ALPHA-EA Preparation Products And Raw materials
Raw materials
Preparation Products
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