6-AMino-4-chloro-nicotinic acid
- Product Name
- 6-AMino-4-chloro-nicotinic acid
- CAS No.
- 1060808-94-7
- Chemical Name
- 6-AMino-4-chloro-nicotinic acid
- Synonyms
- 6-AMino-4-chloro-nicotinic acid;6-Amino-4-chloropyridin-3-carboxylic acid;6-amino-4-chloropyridine-3-carboxylic acid;6-AMino-4-chloro-3-pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 6-amino-4-chloro-;α-D-Glucopyranuronicacid,methylester,2,3,8-triacetate
- CBNumber
- CB52642368
- Molecular Formula
- C6H5ClN2O2
- Formula Weight
- 172.57
- MOL File
- 1060808-94-7.mol
6-AMino-4-chloro-nicotinic acid Property
- Boiling point:
- 383.1±42.0 °C(Predicted)
- Density
- 1.577±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 1.65±0.25(Predicted)
- Appearance
- White to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1983DW
- Product name
- 6-Amino-4-chloronicotinicacid
- Packaging
- 50mg
- Price
- $204
- Updated
- 2021/12/16
- Product number
- A223040
- Product name
- 6-Amino-4-chloronicotinicacid
- Purity
- 97%
- Packaging
- 50mg
- Price
- $107
- Updated
- 2021/12/16
- Product number
- A223040
- Product name
- 6-Amino-4-chloronicotinicacid
- Purity
- 97%
- Packaging
- 100mg
- Price
- $107
- Updated
- 2021/12/16
- Product number
- A223040
- Product name
- 6-Amino-4-chloronicotinicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- A223040
- Product name
- 6-Amino-4-chloronicotinicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $243
- Updated
- 2021/12/16
6-AMino-4-chloro-nicotinic acid Chemical Properties,Usage,Production
Synthesis
670253-38-0
1060808-94-7
General procedure for the synthesis of 4-chloro-6-aminonicotinic acid from 6-amino-4-chloronicotinonitrile: Concentrated sulfuric acid (98%, 0.5 mL) was slowly added dropwise to a stirring suspension of 6-amino-4-chloronicotinonitrile (0.020 g, 0.130 mmol) in water (1 mL). The reaction mixture was heated to 100 °C and maintained for 18 hours. Upon completion of the reaction, it was cooled to room temperature and slowly added dropwise to a saturated sodium bicarbonate solution (2 mL) containing ice and the pH was adjusted to about 2. The resulting precipitate was collected by filtration, washed with water (2 mL), and subsequently air-dried to yield 4-chloro-6-aminonicotinic acid (0.019 g, 0.110 mmol, 84% yield) as a colorless powder, [M + H]+ m/z = 173.0.
References
[1] Patent: WO2013/91011, 2013, A1. Location in patent: Page/Page column 64; 65
[2] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 31 - 38
6-AMino-4-chloro-nicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-AMino-4-chloro-nicotinic acid manufacturers
- Product
- 6-AMino-4-chloro-nicotinic acid 1060808-94-7
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2019-12-20