SGI-110

Product Name: SGI-110
CAS No.: 929901-49-5
Chemical Name: SGI-110
Synonyms: SGI-110;CS-1302;Guadecitabine;SGI110;SGI 110;SGI-110 Guadecitabine;SGI-110 ammonium salt;2'-Deoxy-5-azacytidylyl-(3'-5')-2'-deoxyguanosine;Guanosine, 2'-deoxy-5-azacytidylyl-(3'→5')-2'-deoxy-
CBNumber: CB52658202
Molecular Formula: C18H24N9O10P
Formula Weight: 557.41
MOL File: 929901-49-5.mol

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SGI-110 Property

Boiling point:: 956.4±75.0 °C(Predicted)
Density: 2.24±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C,unstable in solution, ready to use.
solubility: H2O
form: Powder
pka: 1.37±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC6313
Product name: Guadecitabine（SGI-110）
Purity: 98%
Packaging: 25mg
Price: $2300
Updated: 2021/12/16

DC Chemicals

Product number: DC6313
Product name: Guadecitabine（SGI-110）
Purity: 98%
Packaging: 50mg
Price: $3600
Updated: 2021/12/16

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SGI-110 Chemical Properties,Usage,Production

Uses

SGI 110, is a DNA methyltransferases (DNMT) inhibitor.

in vivo

Guadecitabine (S110) is effective at retarding tumor growth. While the tumors do not shrink in size with Guadecitabine treatment, they experience very minimal growth while the tumors treated with PBS only show substantial growth. In addition, Guadecitabine induces much less toxicity as determined by mouse weight changes when given subcutaneously (SQ) compare to that with IP injections^[3].

target

DNA Methyltransferase

IC 50

DNA Methyltransferase

SGI-110 Preparation Products And Raw materials

Raw materials

Preparation Products

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SGI-110 Suppliers

CHINA 34 United States 3 Global 37

Chembest Research Laboratories Limited

Tel: +86-21-20908456
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Jinan Trio PharmaTech Co., Ltd.

Tel: 0531-88811783
Fax: +86 (531) 55696010 QQ 1762738062
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NCE Biomedical Co.,Ltd.

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Country: China
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Intelligence Pharm Science(Shanghai) Co., Ltd.

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Shanghai Synchem Pharma Co., ltd

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Email: synchempharma@aliyun.com
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SPIRO PHARMA

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ShangHai Biochempartner Co.,Ltd

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Jinan elephant international trading co., LTD

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Amadis Chemical Company Limited

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Shanghai Biopharmaleader Co., Ltd.

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Fax: +86 (21) 5775-8967
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929901-49-5, SGI-110Related Search:

SGI-110

2'-Deoxy-5-azacytidylyl-(3'-5')-2'-deoxyguanosine

Guadecitabine

SGI110;SGI 110

CS-1302

Guanosine, 2'-deoxy-5-azacytidylyl-(3'→5')-2'-deoxy-

SGI-110 ammonium salt

SGI-110 Guadecitabine

929901-49-5

C18H24N9O10P