KN92 phosphate
- Product Name
- KN92 phosphate
- CAS No.
- 1135280-28-2
- Chemical Name
- KN92 phosphate
- Synonyms
- CS-1093;KN92-H3PO4;KN 92; KN92;KN92 phosphate;KN 92 phosphate;KN-92 (phosphate);N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide phosphate;KN92 phosphate,derivative,inactive,KN 92 phosphate,control,Inhibitor,experimental,KN-92,KN 92,inhibit,KN92,analog
- CBNumber
- CB52666645
- Molecular Formula
- C24H28ClN2O7PS
- Formula Weight
- 554.980081
- MOL File
- 1135280-28-2.mol
KN92 phosphate Property
- storage temp.
- = -70C
- solubility
- ≥25 mg/mL in DMSO; insoluble in H2O; ≥43.1 mg/mL in EtOH with gentle warming
- form
- Viscous liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 422709
- Product name
- KN-92 - CAS 1135280-28-2 - Calbiochem<br />KN-92, CAS 1135280-28-2, is useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM Kinase II inhibitor.
- Packaging
- 1mg
- Price
- $187
- Updated
- 2024/03/01
- Product number
- 5.08314
- Product name
- InSolution KN-92 - CAS 1135280-28-2 - Calbiochem
- Packaging
- 500μg
- Price
- $94.3
- Updated
- 2023/01/07
- Product number
- K653503
- Product name
- KN-92
- Packaging
- 2.5mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- A3531
- Product name
- KN-92phosphate
- Packaging
- 10mg
- Price
- $339
- Updated
- 2021/12/16
- Product number
- A3531
- Product name
- KN-92phosphate
- Packaging
- 50mg
- Price
- $986
- Updated
- 2021/12/16
KN92 phosphate Chemical Properties,Usage,Production
Uses
KN-92 is a useful negative control for KN-93.
General Description
Useful as a negative control for KN-93 (Cat. No. 422708), a Ca2+/CaM kinase II inhibitor.
Biological Activity
kn-92 is the inactive analog of ca2+/calmodulin-dependent kinase ii (camkii) inhibitor kn-93. kn-92 has been often used as negative control for kn-93.kn-92 significantly reduced the sustained current amplitudes at the end of the 5-s depolarizing pulses of a wide range of kv channels such as kv1.5 and kv1.2 [1].
Biochem/physiol Actions
Cell permeable: yes
storage
Store at -20°C
References
[1]. rezazadeh s, claydon tw, fedida d.kn-93(2-[n-(2-hydroxyethyl)]-n-(4-methoxybenzenesulfonyl)]amino-n-(4-chlorocinnamyl)-n-methylbenzylamine), a calcium/calmodulin-dependent protein kinase ii inhibitor, is a direct extracellular blocker of voltage-gated potassium channels.j pharmacolexpther. 2006 apr;317(1):292-9.