TAS-102

Product Name: TAS-102
CAS No.: 733030-01-8
Chemical Name: TAS-102
Synonyms: TAS-102;TAS 102 (2:1);TAS102; TAS 102;TAS-102 (LONSURF);TAS-102(TIPIRACIL, TRIFLURIDINE);TAS-102 (Trifluridine/Tipiracil HCl);Trifluridine-tipiracil hydrochloride mixt.;Tipiracil hydrochloride-trifluridine mixt.;rifluridine-tipiracil hydrochloride mixture;TRIFLURIDINE-TIPIRACIL HYDROCHLORIDE MIXTURE
CBNumber: CB52667622
Molecular Formula: C19H23Cl2F3N6O7
Formula Weight: 575.32
MOL File: 733030-01-8.mol

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TAS-102 Property

Melting point:: 170-172°C
storage temp.: Hygroscopic, Refrigerator, under inert atmosphere
solubility: DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Carc. 2
Muta. 2
Repr. 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H341Suspected of causing genetic defects

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2707
Product name: TAS-102
Purity: ≥98% (HPLC)
Packaging: 10MG
Price: $145
Updated: 2026/03/19

Cayman Chemical

Product number: 23932
Product name: TAS 102
Packaging: 5mg
Price: $50
Updated: 2023/01/06

Cayman Chemical

Product number: 23932
Product name: TAS 102
Packaging: 10mg
Price: $94
Updated: 2023/01/06

Cayman Chemical

Product number: 23932
Product name: TAS 102
Packaging: 25mg
Price: $207
Updated: 2023/01/06

Cayman Chemical

Product number: 23932
Product name: TAS 102
Packaging: 50mg
Price: $366
Updated: 2023/01/06

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TAS-102 Chemical Properties,Usage,Production

Uses

TAS 102 (Tipiracil-trifluridine) is a thymidine phosphorylase inhibitor used in chemotherapy treatment of advanced/recurring colorectal cancer.

Biological Activity

Anti cancer, Anti angiogenic

in vivo

Trifluridine/tipiracil hydrochloride mixture (150 mg/kg/day; p.o.; twice a day for 14 days) prevents body weight loss and reduces the relative tumor volume in colorectal cancer and gastric cancer mice models^[2].

Animal Model:	Male nude mice bearing KM12C, KM12C/5-FU, DLD-1, DLD-1/5-FU, and SC-2 cells^[2]
Dosage:	150 mg/kg/day
Administration:	p.o.; twice a day for 14 days
Result:	Prevented body weight loss and reduced the relative tumor volume in colorectal cancer and gastric cancer mice models.

TAS-102 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAS-102 Suppliers

China 77 United States 11 Global 88

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4790
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3505
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4827
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 9955
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29661
Advantage: 68

733030-01-8, TAS-102Related Search:

Futibatinib TAS6417 TAS0728 TAS-301 TAS-116

TAS-102

Tipiracil hydrochloride-trifluridine mixt.

TRIFLURIDINE-TIPIRACIL HYDROCHLORIDE MIXTURE

TAS-102(Tipiracil hydrochloride-trifluridine mixt)

Trifluridine-tipiracil hydrochloride mixt.

TAS-102(TIPIRACIL, TRIFLURIDINE)

TAS-102 (LONSURF)

TAS102; TAS 102

TAS 102 (2:1)

TAS-102 (Trifluridine/Tipiracil HCl)

inhibit,Thymidylate Synthase,Nucleoside Antimetabolite/Analog,oral,Inhibitor,FTD,DNA,nucleoside,antitumor,TPI,Trifluridine/tipiracil hydrochloride mixture

rifluridine-tipiracil hydrochloride mixture

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione mixt. with 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione (1:1) hydrochloride

Trifluridine/tipiracil hydrochloride mixture, 10 mM in DMSO

733030-01-8

C10H11F3N2O5C9H11ClN4O2HCl