3,4,5-Trichlorobenzaldehyde
- Product Name
- 3,4,5-Trichlorobenzaldehyde
- CAS No.
- 56961-76-3
- Chemical Name
- 3,4,5-Trichlorobenzaldehyde
- Synonyms
- 3,4,5-Trichlorobenzaldehyde;Benzaldehyde, 3,4,5-trichloro-
- CBNumber
- CB52680391
- Molecular Formula
- C7H3Cl3O
- Formula Weight
- 209.46
- MOL File
- 56961-76-3.mol
3,4,5-Trichlorobenzaldehyde Property
- Melting point:
- 90-91 °C
- Boiling point:
- 280.5±35.0 °C(Predicted)
- Density
- 1.529±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Dichloromethane; Ethyl Acetate
- form
- Solid
- color
- White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T774483
- Product name
- 3,4,5-Trichlorobenzaldehyde
- Packaging
- 25mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- T774483
- Product name
- 3,4,5-Trichlorobenzaldehyde
- Packaging
- 250mg
- Price
- $495
- Updated
- 2021/12/16
- Product number
- 1494CV
- Product name
- 3,4,5-Trichlorobenzaldehyde
- Packaging
- 5g
- Price
- $498
- Updated
- 2021/12/16
- Product number
- 56961763
- Product name
- 3,4,5-Trichlorobenzaldehyde
- Packaging
- 250mg
- Price
- $504
- Updated
- 2021/12/16
- Product number
- CD12060063
- Product name
- 3,4,5-Trichlorobenzaldehyde
- Purity
- 95+%
- Packaging
- 10g
- Price
- $706
- Updated
- 2021/12/16
3,4,5-Trichlorobenzaldehyde Chemical Properties,Usage,Production
Uses
3,4,5-Trichlorobenzaldehyde is an intermediate in synthesizing 1,2,3-Trichloro-5-methylbenzene (T774368), a useful in calculating 21 physical properties of organic compounds strictly from molecular structure.
Synthesis
21928-51-8
68-12-2
56961-76-3
Example 56 Preparation of 3,4,5-trichlorobenzaldehyde (C96): first, a 500 mL round-bottomed flask was dried in an oven and flushed with nitrogen. The flask was equipped with a pressure-balanced addition funnel. 5-Bromo-1,2,3-trichlorobenzene (10.0 g, 38.4 mmol) was dissolved in tetrahydrofuran (100 mL), and the resulting solution was cooled in an ice bath under nitrogen protection. Isopropylmagnesium chloride (2M tetrahydrofuran solution, 21.1 mL, 42.3 mmol) was slowly added dropwise over a period of 15 minutes through the addition funnel with full stirring. After the dropwise addition, stirring was continued for 0.5 hours. Subsequently, N,N-dimethylformamide (3.72 mL, 48.0 mmol) was added to the dark solution under stirring. After 0.5 hours of reaction, 1N hydrochloric acid (100 mL) was added under stirring to terminate the reaction. The organic and aqueous layers were separated and the organic layer was washed with brine. The combined aqueous layers were extracted with ether and the combined organic phases were dried with anhydrous sodium sulfate, filtered and concentrated to give the title compound as a white solid (10:1 mixture of the title compound with 1,2,3-trichlorobenzene, 7.96 g, 99% yield). The product was confirmed by 1H NMR (CDCl3): δ 9.91 (s, 1H), 7.88 (s, 2H); EIMS m/z 209 ([M]+).
References
[1] Patent: WO2016/168059, 2016, A1. Location in patent: Page/Page column 84-85
[2] Patent: US2018/98541, 2018, A1. Location in patent: Paragraph 1464-1465
3,4,5-Trichlorobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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