benzo[c][1,2]oxaborole-1,6(3H)-diol
- Product Name
- benzo[c][1,2]oxaborole-1,6(3H)-diol
- CAS No.
- 1196473-37-6
- Chemical Name
- benzo[c][1,2]oxaborole-1,6(3H)-diol
- Synonyms
- EOS-60533;2,1-Benzoxaborole-1,6(3H)-diol;Benzo[c][1,2]oxaborole-1,6(3H);1-hydroxy-3H-2,1-benzoxaborol-6-ol;benzo[c][1,2]oxaborole-1,6(3H)-diol;1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-ol;2,1-Benzoxaborol-6-ol, 1,3-dihydro-1-hydroxy-;6-hydroxyl-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- CBNumber
- CB52684506
- Molecular Formula
- C7H7BO3
- Formula Weight
- 149.94
- MOL File
- 1196473-37-6.mol
benzo[c][1,2]oxaborole-1,6(3H)-diol Property
- Melting point:
- 133-135 °C
- Boiling point:
- 328.6±52.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 7.18±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D6275
- Product name
- Benzo[c][1,2]oxaborole-1,6(3H)-diol
- Packaging
- 250MG
- Price
- $189
- Updated
- 2025/07/31
- Product number
- D6275
- Product name
- Benzo[c][1,2]oxaborole-1,6(3H)-diol
- Packaging
- 1G
- Price
- $642
- Updated
- 2025/07/31
- Product number
- 119592
- Product name
- Benzo[c][1,2]oxaborole-1,6(3H)-diol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $810
- Updated
- 2021/12/16
- Product number
- 3393AA
- Product name
- Benzo[c][1,2]oxaborole-1,6(3H)-diol
- Packaging
- 5g
- Price
- $2179
- Updated
- 2021/12/16
- Product number
- CHM0391819
- Product name
- BENZO[C][1,2]OXABOROLE-1,6(3H)-DIOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.63
- Updated
- 2021/12/16
benzo[c][1,2]oxaborole-1,6(3H)-diol Chemical Properties,Usage,Production
Synthesis
1222010-47-0
1196473-37-6
General procedure for the synthesis of benzo[c][1,2]oxaborolane-1,6(3H)-diol from 6-(benzyloxy)benzo[C][1,2]oxaborolane-1(3H)-ol: 6-(benzyloxy)benzo[C][1,2]oxaborolane-1(3H)-ol (13 mmol) was dissolved in methanol (300 mL). To this solution was added 10% palladium/carbon catalyst (200 mg) under nitrogen protection. The reaction mixture was evacuated under vacuum three times and charged with hydrogen, followed by stirring the reaction overnight at room temperature. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated by rotary evaporation. The residue was purified by recrystallization to afford benzo[c][1,2]oxaborolane-1,6(3H)-diol (1.98 mg, 98% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 9.29 (s, 1H), 9.04 (s, 1H), 7.18 (d, J=8.4Hz, 2H), 6.87 (dd, J=8.1, 2.4Hz, 1H), 4.86 (s, 2H) ppm. melting point was 133-135 °C.
References
[1] Patent: WO2011/49971, 2011, A1. Location in patent: Page/Page column 58
[2] Patent: WO2010/45503, 2010, A1. Location in patent: Page/Page column 154
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 5, p. 1276 - 1287
[4] ACS Medicinal Chemistry Letters, 2010, vol. 1, # 4, p. 165 - 169
[5] Patent: WO2014/149793, 2014, A1. Location in patent: Page/Page column 37
benzo[c][1,2]oxaborole-1,6(3H)-diol Preparation Products And Raw materials
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View Lastest Price from benzo[c][1,2]oxaborole-1,6(3H)-diol manufacturers
- Product
- benzo[c][1,2]oxaborole-1,6(3H)-diol 1196473-37-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-09