5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

Product Name: 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester
CAS No.: 24269-96-3
Chemical Name: 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester
Synonyms: βARK1 Inhibitor;GRK2 Inhibitor 1;GRK-2 Inhibitor,GRK2 Inhibitor;beta-Adrenergic Receptor Kinase 1 Inhibitor;Methyl (E)-5-(2-(5-nitrofuran-2-yl)vinyl)furan-2-carboxylate;betaARK1 Inhibitor, beta-Adrenergic Receptor Kinase 1 inhibitor;5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester;2-Furancarboxylic acid, 5-[2-(5-nitro-2-furanyl)ethenyl]-, methyl ester
CBNumber: CB52695425
Molecular Formula: C12H9NO6
Formula Weight: 263.2
MOL File: 24269-96-3.mol

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5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Property

Melting point:: 139-140 °C
Boiling point:: 408.4±45.0 °C(Predicted)
Density: 1.400±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Acetone (Slightly), Methanol (Slightly)
form: Solid
color: Pale Yellow to Yellow
Sensitive: Light Sensitive
InChI: 1S/C12H9NO6/c1-17-12(14)10-6-4-8(18-10)2-3-9-5-7-11(19-9)13(15)16/h2-7H,1H3/b3-2+
InChIKey: YDJPHSNZGRVPCK-NSCUHMNNSA-N
SMILES: [N+](=O)([O-])c1[o]c(cc1)\C=C\c2[o]c(cc2)C(=O)OC

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Safety

WGK Germany: WGK 1
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 182200
Product name: βARK1 Inhibitor - CAS 24269-96-3 - Calbiochem
Packaging: 5MG
Price: $163
Updated: 2025/07/31

Cayman Chemical

Product number: 21751
Product name: βARK1 Inhibitor
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 21751
Product name: βARK1 Inhibitor
Packaging: 25mg
Price: $618
Updated: 2024/03/01

Cayman Chemical

Product number: 21751
Product name: βARK1 Inhibitor
Packaging: 5mg
Price: $142
Updated: 2024/03/01

Cayman Chemical

Product number: 21751
Product name: βARK1 Inhibitor
Packaging: 10mg
Price: $266
Updated: 2024/03/01

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5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Chemical Properties,Usage,Production

Uses

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.

Biological Activity

Cell permeable: no', 'Primary Target
βARK1 (β-Adrenergic Receptor Kinase 1)', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 126 μM against βARK1 (β-Adrenergic Receptor Kinase 1)

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Suppliers

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24269-96-3, 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl EsterRelated Search:

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

beta-Adrenergic Receptor Kinase 1 Inhibitor

2-Furancarboxylic acid, 5-[2-(5-nitro-2-furanyl)ethenyl]-, methyl ester

βARK1 Inhibitor

GRK-2 Inhibitor,GRK2 Inhibitor

Methyl (E)-5-(2-(5-nitrofuran-2-yl)vinyl)furan-2-carboxylate

GRK2 Inhibitor 1

betaARK1 Inhibitor, beta-Adrenergic Receptor Kinase 1 inhibitor

24269-96-3

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