CP-868388

Product Name: CP-868388
CAS No.: 702681-67-2
Chemical Name: CP-868388
Synonyms: CP-868388;(-)-CP-868388;UNII-999KY5ZIGB;CP-868388 free base;(S)-2-(3-(1-((4-Isopropylbenzyloxy)carbonyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid;2-methyl-2-{3-[(3S)-1-({[4-(propan-2-yl)phenyl]methoxy}carbonyl)piperidin-3-yl]phenoxy}propanoic acid;1-Piperidinecarboxylic acid, 3-[3-(1-carboxy-1-methylethoxy)phenyl]-, 1-[[4-(1-methylethyl)phenyl]methyl] ester, (3S)-
CBNumber: CB52695733
Molecular Formula: C26H33NO5
Formula Weight: 439.54
MOL File: 702681-67-2.mol

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CP-868388 Property

Boiling point:: 584.6±50.0 °C(Predicted)
Density: 1.161±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥30mg/mL
form: powder
pka: 3.28±0.10(Predicted)
color: white to off-white
optical activity: [α]/D -50 to -65°, c = 0.2 in methanol

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Safety

Hazard Codes: T,N
Risk Statements: 25-50/53
Safety Statements: 45-60-61
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0149
Product name: CP-868388
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $524
Updated: 2025/07/31

Sigma-Aldrich

Product number: PZ0149
Product name: CP-868388
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $306
Updated: 2024/03/01

ChemScene

Product number: CS-0066296
Product name: CP-868388freebase
Packaging: 5mg
Price: $280
Updated: 2021/12/16

ChemScene

Product number: CS-0066296
Product name: CP-868388freebase
Packaging: 10mg
Price: $440
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 50429
Product name: CP-868388
Packaging: 10mg
Price: $680
Updated: 2021/12/16

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CP-868388 Chemical Properties,Usage,Production

Uses

CP-868388 is a potent PPARα agonist with a Ki of 10.8 nM for therapeutic use as hypolipemics, antidiabetics.

Biological Activity

CP-868388 is a potent PPARα agonist with a Ki of 10.8 nM.

in vivo

CP-868388 (0-3 mg/kg; oral gavage; once daily; for 2 days; male B6/CBF1J mice) treatment shows a robust and highly significant decrease in circulating plasma triglycerides. Triglyceride lowering is dose-dependent with the greatest efficacy achieved at the 3.0 mg/kg dose, with triglyceride decreases of ~50%^[1].

Animal Model:	Male B6/CBF1J mice^[1]
Dosage:	0 mg/kg, 0.3 mg/kg, 1 mg/kg, 3 mg/kg
Administration:	Oral gavage; once daily; for 2 days
Result:	Demonstrated a robust and highly significant decrease in circulating plasma triglycerides.

IC 50

hPPARα: 10.8 nM (Ki); hPPARγ: 3.47 μM (Ki)

CP-868388 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP-868388 Suppliers

Canada 1 China 14 United States 4 USA 1 Global 20

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
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Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Block Chemical Technology (Shanghai) Co., Ltd.

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 10034
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
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Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
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Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
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702681-67-2, CP-868388Related Search:

CP-868388

(S)-2-(3-(1-((4-Isopropylbenzyloxy)carbonyl)piperidin-3-yl)phenoxy)-2-methylpropanoic acid

CP-868388 free base

1-Piperidinecarboxylic acid, 3-[3-(1-carboxy-1-methylethoxy)phenyl]-, 1-[[4-(1-methylethyl)phenyl]methyl] ester, (3S)-

(-)-CP-868388

UNII-999KY5ZIGB

2-methyl-2-{3-[(3S)-1-({[4-(propan-2-yl)phenyl]methoxy}carbonyl)piperidin-3-yl]phenoxy}propanoic acid

702681-67-2

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