ChemicalBook > CAS DataBase List > 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid

4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid

Product Name
4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid
CAS No.
1187954-57-9
Chemical Name
4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid
Synonyms
FEXOFEDINE IMP-G;fexofenadine Imp-G;Fexofenadine EP Imp G;FEXOFEDINE IMPURITY G;Fexofenadine EP Impurity G;Fexofenadine EP Impurity 7;BRVDCQYIFNJGSU-UHFFFAOYSA-N;Fexofenadine Impurity G HCl;FEXOFENADINE HYDROCHLORIDE EP;Fexofenadine Related Compound G
CBNumber
CB52700260
Molecular Formula
C32H37NO3
Formula Weight
483.64
MOL File
1187954-57-9.mol
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4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid Property

Melting point:
203-206°C
Boiling point:
681.4±55.0 °C(Predicted)
Density 
1.144±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.43±0.10(Predicted)
color 
White to Off-White
Major Application
pharmaceutical small molecule
InChIKey
BRVDCQYIFNJGSU-UHFFFAOYSA-N
SMILES
c1(C(C)(C)C(O)=O)ccc(C(O)CCCN2CC/C(=C(\c3ccccc3)/c3ccccc3)/CC2)cc1
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR9097
Product name
4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid
Purity
certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Packaging
50mg
Price
$665
Updated
2026/03/19
TRC
Product number
D492020
Product name
4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneaceticAcid
Packaging
10mg
Price
$180
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0294130
Product name
FEXOFENADINE IMPURITY-G
Purity
95.00%
Packaging
5MG
Price
$495.51
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
64635
Product name
4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneaceticAcid
Packaging
100mg
Price
$2200
Updated
2021/12/16
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4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid Chemical Properties,Usage,Production

Uses

4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic acid is an impurity of fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.

4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid Suppliers

Perida Pharmaceutical Co., Ltd.
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1187954-57-9, 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic AcidRelated Search:


  • BRVDCQYIFNJGSU-UHFFFAOYSA-N
  • Fexofenadine hydrochloride impurity G (EP)
  • 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid
  • Fexofenadine EP Impurity G
  • Fexofenadine Impurity 7(Fexofenadine EP Impurity G)
  • Fexofenadine Related Compound G
  • Fexofenadine EP Imp G
  • Fexofenadine Hydrochloride EP Impurity G
  • FEXOFENADINE HYDROCHLORIDE EP
  • Benzeneacetic acid, 4-[4-[4-(diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-
  • 2-(4-(4-(4-(diphenylmethylene)piperidin-1-yl)-1-hydroxybutyl)phenyl)-2-methylpropanoic acid
  • fexofenadine Imp-G
  • 2-[4-[(1RS)-4-[4-(diphenylmethylidene)piperidin-1-yl]-1- hydroxybutyl]phenyl]-2-methylpropanoic acid
  • 2-(4-(4-(4-(Diphenylmethylene)piperidin-1-yl)-1-hydroxybutyl)phenyl)-2-methylpropanoic acid (Fexofenadine Impurity)
  • FEXOFEDINE IMP-G
  • FEXOFEDINE IMPURITY G
  • Fexofenadine EP Impurity 7
  • 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid, CAS 1187954-57-9
  • 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid
  • Fexofenadine Impurity G HCl
  • 1187954-57-9