di(Atorvastatin-d5) CalciuM Salt

Product Name: di(Atorvastatin-d5) CalciuM Salt
CAS No.: 222412-82-0
Chemical Name: di(Atorvastatin-d5) CalciuM Salt
Synonyms: D5-Atorvastatin Calcium;[2H5]-Atorvastatin Calcium;Atorvastatin-d5 hemicalcium;Atorvastatin calcium salt-[d5];di(Atorvastatin-d5) CalciuM Salt;Atorvastatin D5 calciumQ: What is Atorvastatin D5 calcium Q: What is the CAS Number of Atorvastatin D5 calcium Q: What is the storage condition of Atorvastatin D5 calcium Q: What are the applications of Atorvastatin D5 calcium
CBNumber: CB52708842
Molecular Formula: C132H122Ca3D10F4N8O20-2
Formula Weight: 2356.79131058
MOL File: 222412-82-0.mol

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di(Atorvastatin-d5) CalciuM Salt Property

storage temp.: Store at -20°C
solubility: DMF: 25 mg/ml,DMSO: 15 mg/ml,Ethanol: 0.50 mg/ml
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25043
Product name: Atorvastatin-d5 (calcium salt)
Purity: ≥99% deuterated forms (d1 -d3)
Packaging: 500μg
Price: $178
Updated: 2024/03/01

Cayman Chemical

Product number: 25043
Product name: Atorvastatin-d5 (calcium salt)
Purity: ≥99% deuterated forms (d1 -d3)
Packaging: 1mg
Price: $336
Updated: 2024/03/01

TRC

Product number: A791754
Product name: Atorvastatin-d5CalciumSalt
Packaging: 0.5mg
Price: $175
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D49605
Product name: di(Atorvastatin-d5)CalciumSalt
Packaging: 1mg
Price: $640
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D49605
Product name: di(Atorvastatin-d5)CalciumSalt
Packaging: 10mg
Price: $2120
Updated: 2021/12/16

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di(Atorvastatin-d5) CalciuM Salt Chemical Properties,Usage,Production

Uses

di(Atorvastatin-d5) Calcium Salt is the labeled analogue of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

Biological Activity

Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.1 Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.

References

1.Shaw, M.K., Newton, R.S., Sliskovic, D.R., et al.Hep-G2 cells and primary rat hepatocytes differ in their response to inhibitors of HMG-CoA reductaseBiochem. Biophys. Res. Commun.170(2)726-734(1990)

di(Atorvastatin-d5) CalciuM Salt Preparation Products And Raw materials

Raw materials

Preparation Products

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di(Atorvastatin-d5) CalciuM Salt Suppliers

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di(Atorvastatin-d5) CalciuM Salt

[2H5]-Atorvastatin Calcium

Atorvastatin calcium salt-[d5]

Atorvastatin D5 calciumQ: What is Atorvastatin D5 calcium Q: What is the CAS Number of Atorvastatin D5 calcium Q: What is the storage condition of Atorvastatin D5 calcium Q: What are the applications of Atorvastatin D5 calcium

Atorvastatin-d5 hemicalcium

D5-Atorvastatin Calcium

222412-82-0