Mycophenolic acid-<sup>13</sup>C<sub>17</sub>
- Product Name
- Mycophenolic acid-<sup>13</sup>C<sub>17</sub>
- CAS No.
- 1202866-92-9
- Chemical Name
- Mycophenolic acid-<sup>13</sup>C<sub>17</sub>
- Synonyms
- 13C17-Mycophenolic Acid;Mycophenolic acid-13C17 solution ;13C17]-Mycophenolic acid-100μg/mL in ACN;Mycophenolic acid-13C17;Mycophenolic acid 13C17 25 μg/mL in Acetonitrile
- CBNumber
- CB52717691
- Molecular Formula
- C17H20O6
- Formula Weight
- 337.4901
- MOL File
- 1202866-92-9.mol
Mycophenolic acid-<sup>13</sup>C<sub>17</sub> Property
- Flash point:
- 2℃
- storage temp.
- -20°C
- solubility
- Acetonitrile: soluble
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36
- Safety Statements
- 16-36/37
- RIDADR
- UN 1648 3 / PGII
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Mycophenolic acid-<sup>13</sup>C<sub>17</sub> Chemical Properties,Usage,Production
Uses
Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. DOI:10.1177/1071100718790255
[2] Sophie Domhan, et al. Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid. Mol Cancer Ther.?2008 Jun;7(6):1656-68. DOI:10.1158/1535-7163.MCT-08-0193
[3] Stephen R Welch, et al. Screening and Identification of Lujo Virus Inhibitors Using a Recombinant Reporter Virus Platform. Viruses.?2021 Jun 28;13(7):1255. DOI:10.3390/v13071255
Mycophenolic acid-<sup>13</sup>C<sub>17</sub> Preparation Products And Raw materials
Raw materials
Preparation Products
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