ChemicalBook > CAS DataBase List > 2-Methyl-1,3-cyclopentanedione

2-Methyl-1,3-cyclopentanedione

Product Name
2-Methyl-1,3-cyclopentanedione
CAS No.
765-69-5
Chemical Name
2-Methyl-1,3-cyclopentanedione
Synonyms
1,3-Cyclopentanedione, 2-methyl-;2-Methylcyclopentane-1,3-dione;2-Methyl-1,3-cyclopentadione;-1,3-cycL;2-Methyl-1;METHYLCYCLE-D;2-Methylcyclopentan-1,3-dion;2-METHYLCYCLOPENTAN-1,3-DIONE;2-Methyl-1,3-dioxocyclopentane;2-METHYL-1,3-CYCLOPENTANEDIONE
CBNumber
CB5272422
Molecular Formula
C6H8O2
Formula Weight
112.13
MOL File
765-69-5.mol
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2-Methyl-1,3-cyclopentanedione Property

Melting point:
212-215 °C (lit.)
Boiling point:
213°C (estimate)
Density 
1.0795 (rough estimate)
refractive index 
1.4550 (estimate)
storage temp. 
Store below +30°C.
solubility 
Solubility in hot Methanol (almost transparency).
pka
10.83±0.20(Predicted)
form 
Crystalline Powder
color 
Light beige to tan
PH
2.95 at 24.7℃ and 10g/L
BRN 
1237255
InChIKey
HXZILEQYFQYQCE-UHFFFAOYSA-N
LogP
-0.8 at 30℃ and pH7.66
CAS DataBase Reference
765-69-5(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Cyclopentanedione, 2-methyl-(765-69-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29142900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
117021
Product name
2-Methyl-1,3-cyclopentanedione
Purity
99%
Packaging
5g
Price
$25.46
Updated
2025/07/31
Sigma-Aldrich
Product number
117021
Product name
2-Methyl-1,3-cyclopentanedione
Purity
99%
Packaging
25g
Price
$54.81
Updated
2025/07/31
Sigma-Aldrich
Product number
8.10504
Product name
2-Methyl-1,3-cyclopentanedione
Purity
for synthesis
Packaging
10g
Price
$64.1
Updated
2022/05/15
TCI Chemical
Product number
M0901
Product name
2-Methyl-1,3-cyclopentanedione
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$29
Updated
2025/07/31
TCI Chemical
Product number
M0901
Product name
2-Methyl-1,3-cyclopentanedione
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$113
Updated
2025/07/31
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2-Methyl-1,3-cyclopentanedione Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE TO TAN CRYSTALLINE POWDER

Uses

2-Methyl-1,3-cyclopentanedione was used as a reactant in the identification and characterization of benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

Uses

2-Methyl-1,3-cyclopentanedione hs been used to explore deoxycholic acid (DCA) induced changes in cell signaling. DCA is a secondary bile acid implicated in numerous pathological conditions. It has also been used in the synthesis of (-)-curcumanolide A and (-)-curcumalactone by aldol-lactonization.

Synthesis Reference(s)

Synthetic Communications, 19, p. 373, 1989 DOI: 10.1080/00397918908050676

Synthesis

614-45-9

3859-41-4

765-69-5

The general procedure for the synthesis of 2-methyl-1,3-cyclopentanedione from 1,3-cyclopentanedione and tert-butyl peroxybenzoate was as follows: 1,3-cyclopentanedione (0.098 g, 1 mmol), tert-butyl peroxybenzoate (0.58 g, 3 mmol), CuCl (0.01 g, 0.1 mmol), and 2 mL of acetic acid were added to a reaction flask, and the reaction was carried out at 120 °C Reaction at 120°C. The progress of the reaction was monitored by thin layer chromatography (TLC) until the reaction was complete. After completion of the reaction, the crude product was purified by column chromatography (eluent ratio of petroleum ether:ethyl acetate = 40:1) to afford the target product 2-methyl-1,3-cyclopentanedione in 68% yield.

References

[1] Patent: CN105254483, 2016, A. Location in patent: Paragraph 0044

2-Methyl-1,3-cyclopentanedione Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Methyl-1,3-cyclopentanedione manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Methyl-1,3-cyclopentanedione 765-69-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-10
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Methyl-1, 3-Cyclopentanedione 765-69-5
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Career Henan Chemical Co
Product
2-Methyl-1,3-cyclopentanedione 765-69-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2019-05-24

765-69-5, 2-Methyl-1,3-cyclopentanedioneRelated Search:

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  • 2-METHYL-1,3-CYCLOPENTANEDIONE(METHYLCYCLO-D)
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  • 2-Methyl-1
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  • 2-Methyl-1,3-cyclopentanedione 99%
  • 2-Methyl-1,3-cyclopentanedione,98%
  • 2-METHYL-1,3-CYCLOPENTANEDIONE FOR SYNTH
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  • 3-hydroxy-2-methyl-1-cyclopent-2-enone
  • 2-Methyl-1,3-cyclopentanedione, 98%, for synthesis
  • 2-Methyl-1,3-cyclopentanedione&gt
  • -1,3-cycL
  • 2-METHYL-1,3-CYCLOPENTANEDIONE / CAS:765-69-5
  • 765-69-5
  • 1120-77-4
  • CH3C5H5O2
  • Building Blocks
  • Carbonyl Compounds
  • C3 to C6
  • Organic Building Blocks
  • Ketones
  • Miscellaneous
  • ketone
  • C3 to C6
  • Carbonyl Compounds
  • Ketones