ChemicalBook > CAS DataBase List > TP-110
TP-110
- Product Name
- TP-110
- CAS No.
- 688737-95-3
- Chemical Name
- TP-110
- Synonyms
- TP-110;L-Valinamide, O-methyl-N-[2-(1-naphthalenyl)acetyl]-L-tyrosyl-N-[1-formyl-2-(4-methoxyphenyl)ethyl]-
- CBNumber
- CB52731150
- Molecular Formula
- C37H41N3O6
- Formula Weight
- 623.74
- MOL File
- 688737-95-3.mol
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TP-110 Property
- Melting point:
- 192-194 °C
- Boiling point:
- 918.0±65.0 °C(Predicted)
- Density
- 1.190±0.06 g/cm3(Predicted)
- pka
- 13.25±0.46(Predicted)
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TP-110 Chemical Properties,Usage,Production
Description
TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases.
TP-110 Preparation Products And Raw materials
Raw materials
Preparation Products
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TP-110 Suppliers
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