ChemicalBook > CAS DataBase List > 4-BroMo-7-chloro-1H-indazole

4-BroMo-7-chloro-1H-indazole

Product Name
4-BroMo-7-chloro-1H-indazole
CAS No.
1186334-61-1
Chemical Name
4-BroMo-7-chloro-1H-indazole
Synonyms
4-BroMo-7-chloro-1H-indazole;1H-Indazole, 4-bromo-7-chloro-
CBNumber
CB52732218
Molecular Formula
C7H4BrClN2
Formula Weight
231.48
MOL File
1186334-61-1.mol
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4-BroMo-7-chloro-1H-indazole Property

Boiling point:
361.6±22.0 °C(Predicted)
Density 
1.878±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
10.71±0.40(Predicted)
Appearance
White to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
B701968
Product name
4-Bromo-7-chloro-1H-indazole
Packaging
50mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
Y3766
Product name
4-Bromo-7-chloro-1H-indazole
Packaging
250mg
Price
$107
Updated
2021/12/16
Ambeed
Product number
A227299
Product name
4-Bromo-7-chloro-1H-indazole
Purity
95%
Packaging
1g
Price
$113
Updated
2021/12/16
AOBChem
Product number
19884
Product name
4-Bromo-7-chloro-1H-indazole
Purity
97%
Packaging
500mg
Price
$120
Updated
2021/12/16
Crysdot
Product number
CD11337964
Product name
4-Bromo-7-chloro-1H-indazole
Purity
95+%
Packaging
1g
Price
$131
Updated
2021/12/16
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4-BroMo-7-chloro-1H-indazole Chemical Properties,Usage,Production

Synthesis

1114809-02-7

1186334-61-1

Step 2: 6-bromo-3-chloro-2-fluorobenzaldehyde (1.0 g, 4.24 mmol) was dissolved in 1,2-dimethoxyethane (DME, 5 mL), followed by hydrazine hydrate (5 mL). The reaction mixture was heated to reflux for 3 h. After completion of the reaction, it was cooled to room temperature. The solvent was evaporated under reduced pressure and water (100 mL) was added to the residue and extracted with ethyl acetate (3 x 30 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford 4-bromo-7-chloro-1H-indazole in 51% yield. Mass spectrum (MS): m/z 230.9 [M + H]+.

References

[1] Patent: WO2009/108838, 2009, A1. Location in patent: Page/Page column 67

4-BroMo-7-chloro-1H-indazole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BroMo-7-chloro-1H-indazole Suppliers

Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

1186334-61-1, 4-BroMo-7-chloro-1H-indazoleRelated Search:


  • 4-BroMo-7-chloro-1H-indazole
  • 1H-Indazole, 4-bromo-7-chloro-
  • 1186334-61-1
  • 186334-61-1