ChemicalBook > CAS DataBase List > 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Product Name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- CAS No.
- 1082041-79-9
- Chemical Name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Synonyms
- 8-Methyl-3,4-dihydro-2H-isoquinolin-1-one;8-Methyl-3,4-dihydroisoquinolin-1(2H)-one;1(2H)-Isoquinolinone, 3,4-dihydro-8-methyl-
- CBNumber
- CB52732748
- Molecular Formula
- C10H11NO
- Formula Weight
- 161.2
- MOL File
- 1082041-79-9.mol
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8-Methyl-3,4-dihydroisoquinolin-1(2H)-one Property
- Boiling point:
- 404.3±45.0 °C(Predicted)
- Density
- 1.111±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.73±0.20(Predicted)
- Appearance
- White to off-white Solid
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N-Bromosuccinimide Price
TRC
- Product number
- M507503
- Product name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Packaging
- 1mg
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- M507503
- Product name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Packaging
- 10mg
- Price
- $75
- Updated
- 2021/12/16
Ark Pharm
- Product number
- P000361463
- Product name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Purity
- 98%
- Packaging
- 1g
- Price
- $184
- Updated
- 2021/12/16
Ark Pharm
- Product number
- P000361463
- Product name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Purity
- 98%
- Packaging
- 100mg
- Price
- $46
- Updated
- 2021/12/16
Ark Pharm
- Product number
- P000361463
- Product name
- 8-Methyl-3,4-dihydroisoquinolin-1(2H)-one
- Purity
- 98%
- Packaging
- 250mg
- Price
- $74
- Updated
- 2021/12/16
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8-Methyl-3,4-dihydroisoquinolin-1(2H)-one Chemical Properties,Usage,Production
Synthesis
116409-35-9
1082041-79-9
8-Methylisoquinolin-1(2H)-one (76a, 1 g, 6.29 mmol) was used as raw material and mixed with 10% Pd/C (0.5 g) in methanol (20 mL). The mixture was subjected to hydrogenation reaction under hydrogen (60 psi) atmosphere at 80°C for 48 hours. Upon completion of the reaction, the reaction mixture was filtered and the solid catalyst was washed with methanol (2 x 20 mL). The filtrate was concentrated under vacuum to afford the target product 8-methyl-3,4-dihydroisoquinolin-1(2H)-one (76b, 1 g, ~100% yield) as a gray solid.
References
[1] Patent: US2014/179667, 2014, A1. Location in patent: Paragraph 0874; 0876
8-Methyl-3,4-dihydroisoquinolin-1(2H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
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