ChemicalBook > CAS DataBase List > CO-1686 intermediate 1

CO-1686 intermediate 1

Product Name
CO-1686 intermediate 1
CAS No.
1374507-25-1
Chemical Name
CO-1686 intermediate 1
Synonyms
ROCI-005;CO-1686 intermediate 1;N-(3-((2-chloro-5-(trifluoromethyl)pyri midin-4-yl)amino)phenyl)acrylamide;N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide;N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide;2-Propenamide, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-
CBNumber
CB52737268
Molecular Formula
C14H10ClF3N4O
Formula Weight
342.7
MOL File
1374507-25-1.mol
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CO-1686 intermediate 1 Property

Boiling point:
519.7±50.0 °C(Predicted)
Density 
1.476±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
pka
13.21±0.70(Predicted)
InChI
InChI=1S/C14H10ClF3N4O/c1-2-11(23)20-8-4-3-5-9(6-8)21-12-10(14(16,17)18)7-19-13(15)22-12/h2-7H,1H2,(H,20,23)(H,19,21,22)
InChIKey
AXMHVOLJINONIM-UHFFFAOYSA-N
SMILES
C(NC1=CC=CC(NC2C(C(F)(F)F)=CN=C(Cl)N=2)=C1)(=O)C=C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A619735
Product name
N-(3-{[2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide
Packaging
250mg
Price
$695
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0620699
Product name
N-(3-(2-CHLORO-5-(TRIFLUOROMETHYL)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE
Purity
95.00%
Packaging
5MG
Price
$499.09
Updated
2021/12/16
Chemenu
Product number
CM167724
Product name
N-(3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity
95+%
Packaging
5g
Price
$561
Updated
2021/12/16
Crysdot
Product number
CD11269935
Product name
N-(3-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity
97%
Packaging
5g
Price
$600
Updated
2021/12/16
Chemenu
Product number
CM167724
Product name
N-(3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
Purity
95+%
Packaging
10g
Price
$935
Updated
2021/12/16
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CO-1686 intermediate 1 Chemical Properties,Usage,Production

Uses

N-(3-{[2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide can be used as potent BTK and JAK3 dual inhibitors.

CO-1686 intermediate 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CO-1686 intermediate 1 Suppliers

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1374507-25-1, CO-1686 intermediate 1Related Search:


  • CO-1686 intermediate 1
  • N-(3-((2-chloro-5-(trifluoromethyl)pyri midin-4-yl)amino)phenyl)acrylamide
  • N-[3-[[2-Chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide
  • N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide
  • ROCI-005
  • 2-Propenamide, N-[3-[[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-
  • 1374507-25-1
  • C14H10ClF3N4O