Intermediate of Rolapitant

Product Name
Intermediate of Rolapitant
CAS No.
205654-80-4
Chemical Name
Intermediate of Rolapitant
Synonyms
Intermediate of Rolapitant;(2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate;Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate;3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID;3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-
CBNumber
CB52743016
Molecular Formula
C23H19NO4
Formula Weight
373.4
MOL File
205654-80-4.mol
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Intermediate of Rolapitant Property

Boiling point:
591.6±50.0 °C(Predicted)
Density 
1.270±0.06 g/cm3(Predicted)
pka
-3.96±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B287516
Product name
(2R,4S)-Benzyl5-oxo-2,4-diphenyloxazolidine-3-carboxylate
Packaging
2.5g
Price
$990
Updated
2021/12/16
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Intermediate of Rolapitant Chemical Properties,Usage,Production

Uses

(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.

Intermediate of Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

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Intermediate of Rolapitant Suppliers

China 7 Global 7
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
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Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd
Tel
+86-021-50929289 86186163093
Fax
-
Email
sales@ypptech.com.cn
Country
China
ProdList
344
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58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
info@afinechem.com
Country
China
ProdList
15396
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58
Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
Email
meishipharma@126.com
Country
China
ProdList
20035
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58
Shaanxi Didu New Material Co., Ltd
Tel
029-63373950 15353716720
Email
1052@dideu.com
Country
China
ProdList
10010
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58
Suzhou Haiben Pharmaceutical Co., Ltd
Tel
14760821013 14760821013
Email
1816280386@qq.com
Country
China
ProdList
8068
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58
Shaanxi Henghan New Materials Co., Ltd
Tel
15619311539
Email
907967238@qq.com
Country
China
ProdList
2572
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58

205654-80-4, Intermediate of RolapitantRelated Search:


  • Intermediate of Rolapitant
  • (2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate
  • 3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-
  • 3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID
  • Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate
  • 205654-80-4