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ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE

Product Name
ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
CAS No.
148550-51-0
Chemical Name
ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
Synonyms
Ethyl 2-(Methylsulfonyl)-5-pyrimidinecarboxylate;ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE;ETHYL 2-(METHYLSULPHONYL)PYRIMIDINE-5-CARBOXYLATE;Ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate 95%;2-(Methylsulfonyl)-5-pyrimidinecarboxylic acid ethyl ester;5-Pyrimidinecarboxylic acid, 2-(methylsulfonyl)-, ethyl ester;ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE ISO 9001:2015 REACH
CBNumber
CB5286362
Molecular Formula
C8H10N2O4S
Formula Weight
230.24
MOL File
148550-51-0.mol
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ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE Property

Boiling point:
407.7±37.0 °C(Predicted)
Density 
1.338±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-4.99±0.22(Predicted)
Appearance
Off-white to yellow Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR55185
Product name
Ethyl2-(methylsulfonyl)pyrimidine-5-carboxylate
Purity
95%
Packaging
100mg
Price
$218
Updated
2021/12/16
Apolloscientific
Product number
OR55185
Product name
Ethyl2-(methylsulfonyl)pyrimidine-5-carboxylate
Purity
95%
Packaging
250mg
Price
$327
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0376240
Product name
ETHYL-2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$501.09
Updated
2021/12/16
Apolloscientific
Product number
OR55185
Product name
Ethyl2-(methylsulfonyl)pyrimidine-5-carboxylate
Purity
95%
Packaging
1g
Price
$754
Updated
2021/12/16
Crysdot
Product number
CD11251854
Product name
Ethyl2-(methylsulfonyl)pyrimidine-5-carboxylate
Purity
95+%
Packaging
5g
Price
$850
Updated
2021/12/16
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ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

73781-88-1

148550-51-0

Step 2: Synthesis of ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate (121); Sulfide 120 (0.424 g, 2.14 mmol) was dissolved in dichloromethane (DCM, 9 mL), and a DCM (9 mL) solution of 3-chloroperoxybenzoic acid (mCPBA, 2.0 g) was slowly added. The reaction mixture was stirred at room temperature for 100 min. Upon completion of the reaction, the reaction was quenched with aqueous Na2S2O3, diluted with DCM and washed with saturated NaHCO3 solution. The organic phase was dried over anhydrous MgSO4, filtered and concentrated to give the target product 121 (0.374 g, 76% yield). [0726] MS: m/z 230.1 (calculated), 230.9 (measured).

References

[1] Synthetic Communications, 1993, vol. 23, # 6, p. 715 - 723
[2] Patent: WO2007/118137, 2007, A1. Location in patent: Page/Page column 105
[3] Chemical Biology and Drug Design, 2016, vol. 87, # 3, p. 472 - 477
[4] Patent: CN106279044, 2017, A. Location in patent: Paragraph 0026; 0030; 0070; 0071
[5] Patent: WO2012/117421, 2012, A1. Location in patent: Page/Page column 44

ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE Suppliers

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
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Bellen Chemistry Co., Ltd.
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Lanzhou Angeli Biochemical Technology Co., Ltd.
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View Lastest Price from ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate 148550-51-0
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12

148550-51-0, ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATERelated Search:


  • 2-(Methylsulfonyl)-5-pyrimidinecarboxylic acid ethyl ester
  • ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE
  • ETHYL 2-(METHYLSULPHONYL)PYRIMIDINE-5-CARBOXYLATE
  • Ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate 95%
  • 5-Pyrimidinecarboxylic acid, 2-(methylsulfonyl)-, ethyl ester
  • ETHYL 2-(METHYLSULFONYL)PYRIMIDINE-5-CARBOXYLATE ISO 9001:2015 REACH
  • Ethyl 2-(Methylsulfonyl)-5-pyrimidinecarboxylate
  • 148550-51-0
  • Pyridines, Pyrimidines, Purines and Pteredines