TMPYP
- Product Name
- TMPYP
- CAS No.
- 36951-72-1
- Chemical Name
- TMPYP
- Synonyms
- TMPY;TMPYP;TMP 1363;TMPyP [=αTMPyP4 tosylate;TMPyP[=α, β,γTMP-1363 tetratosylate;TMPYP ISO 9001:2015 REACH;TMPYP,ultra-highsensitivespectr;Tetrakismethylpiridiniumylporphine
- CBNumber
- CB5294316
- Molecular Formula
- C72H66N8O12S4
- Formula Weight
- 1363.6
- MOL File
- 36951-72-1.mol
TMPYP Property
- Melting point:
- >300℃
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- water: soluble50MM(lit.)
- form
- Purple solid
- color
- Dark red to Dark purple to Dark blue
- Water Solubility
- Soluble to 50 mM in water
- λmax
- 421 nm
- BRN
- 6049195
- Stability:
- Hygroscopic, Light Sensitive
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 323497
- Product name
- 5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
- Purity
- Dye content 97 %
- Packaging
- 100mg
- Price
- $91.2
- Updated
- 2023/06/20
- Product number
- 323497
- Product name
- 5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
- Purity
- Dye content 97 %
- Packaging
- 250mg
- Price
- $193
- Updated
- 2023/06/20
- Product number
- A5014
- Product name
- TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate][Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
- Purity
- >98.0%(N)
- Packaging
- 1g
- Price
- $318
- Updated
- 2024/03/01
- Product number
- A5014
- Product name
- TMPyP [=alpha,beta,gamma,delta-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate][Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
- Purity
- >98.0%(N)
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 18474
- Product name
- TMPyP4 (tosylate)
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $37
- Updated
- 2024/03/01
TMPYP Chemical Properties,Usage,Production
Uses
TMPyP4 is a potent inhibitor of telomerase activity.
Definition
ChEBI: An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.
General Description
5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p toluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O2 luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.
Biological Activity
Cell permeable: no', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 6.5 μM inhibiting human telomerase
storage
Store at +4°C
TMPYP Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TMPYP manufacturers
- Product
- TMPYP 36951-72-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-27