ChemicalBook > CAS DataBase List > 2,3-Dihydro-1-benzofuran-2-carboxylic acid

2,3-Dihydro-1-benzofuran-2-carboxylic acid

Product Name
2,3-Dihydro-1-benzofuran-2-carboxylic acid
CAS No.
1914-60-9
Chemical Name
2,3-Dihydro-1-benzofuran-2-carboxylic acid
Synonyms
AKOS BBS-00006837;2,3-Dihydro-2-benzofurancarboxylic Acid;2,3-dihydro-1-benzofuran-2-carboxylicaci;2,3-DIHYDRO-BENZOFURAN-2-CARBOXYLIC ACID;2-Benzofurancarboxylic acid, 2,3-dihydro-;2,3-Dihydrobenzo[b]furan-2-carboxylic acid;2,3-Dihydro-1-Benzofurane-2-CarboxylicAcid;2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID;(2-methyl-3-imidazo[1,2-a]pyridinyl)methanol;2,3-Dihydro-1-benzofuran-2-carboxylic acid, 2-Carboxy-2,3-dihydrobenzo[b]furan
CBNumber
CB5295409
Molecular Formula
C9H8O3
Formula Weight
164.16
MOL File
1914-60-9.mol
More
Less

2,3-Dihydro-1-benzofuran-2-carboxylic acid Property

Melting point:
116-118
Boiling point:
340.5±31.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
solid
pka
3.17±0.20(Predicted)
color 
White to off-white
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-51-22
Safety Statements 
26-37/39
Hazard Note 
Irritant
HS Code 
29321900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D448695
Product name
2,3-Dihydro-2-benzofurancarboxylicAcid
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
D448695
Product name
2,3-Dihydro-2-benzofurancarboxylicAcid
Packaging
1g
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019347
Product name
2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
1G
Price
$721.57
Updated
2021/12/16
AK Scientific
Product number
W4106
Product name
2,3-Dihydrobenzofuran-2-carboxylicacid
Packaging
25g
Price
$801
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019347
Product name
2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5G
Price
$1168.42
Updated
2021/12/16
More
Less

2,3-Dihydro-1-benzofuran-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

This compound is the starting material in the synthesis of (dihydro)benzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 24, p. 495, 1987 DOI: 10.1002/jhet.5570240236

Synthesis

496-41-3

1914-60-9

a) Synthesis of (R,S)-2,3-dihydro-benzofuran-2-carboxylic acid (54a): commercially available benzofuran-2-carboxylic acid (Aldrich Chemical Company, 27 g, 167.7 mmol) was dissolved in ethyl acetate (300 mL). The hydrogenation reaction was catalyzed by 10% Pd/C (20 g) at 65-70 psi hydrogen pressure for 2 days. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated. A solvent mixture of ethyl acetate-hexane (1:6) was added to the residue for recrystallization. Filtration afforded benzodihydrofuran-2-carboxylic acid as a crystalline solid (20.23 g, 74% yield). Melting point: 116-117 °C. 1H NMR (300 MHz, CDCl3) δ: 11.05 (brs, 1H), 7.17 (m, 2H), 6.91 (m, 2H), 5.24 (dd, 1H), 3.63 (dd, 1H), 3.42 (dd, 1H).

References

[1] Patent: US2005/54630, 2005, A1. Location in patent: Page/Page column 42
[2] Justus Liebigs Annalen der Chemie, 1883, vol. 216, p. 169
[3] Chemische Berichte, 1906, vol. 39, p. 496
[4] Farmaco, 1998, vol. 53, # 12, p. 764 - 772
[5] Patent: US2008/200540, 2008, A1. Location in patent: Page/Page column 18

2,3-Dihydro-1-benzofuran-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,3-Dihydro-1-benzofuran-2-carboxylic acid Suppliers

Belgium 1 China 88 Europe 1 Germany 3 India 2 Ukraine 2 United Kingdom 4 United States 14 Global 115
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ZEROSCHEM.CO.,LTD.
Tel
10-61256048 13810278579
Fax
+86 10 61256049
Email
sales@zeroschem.com
Country
China
ProdList
1371
Advantage
59
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
QINGDAO CARELONGPHARMATECH CO.,LTD
Tel
0532-0532-88191853 13061484198
Fax
+86-532-88191853
Email
sales@carelongchem.com
Country
China
ProdList
439
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2151
Advantage
55
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
ShangHai AmK Pharmaceutical Technology Co., Ltd.
Tel
微信 17321281695 18019252918
Fax
17321281695
Email
sale@amkchem.com
Country
China
ProdList
15136
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Shanghai Carlow Chemicals Co., Ltd.
Tel
21-33526724 18930996265
Fax
+86 21 37023730
Email
info@carlowchem.com
Country
China
ProdList
1969
Advantage
50
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9287
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Biokitchen
Tel
021-021-021-31663258 13795219287
Fax
021-31663258
Email
donghuanwen@126.com
Country
China
ProdList
8816
Advantage
58
Wuxi AppTec
Tel
022-59987777 13552403979
Email
jia_guoqiang@wuxiapptec.com
Country
China
ProdList
22345
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9722
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
14948
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9992
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
Advantage
58
Tianjin Nuokang Pharmaceutical Technology Co., Ltd.
Tel
022-23989838 13810451150
Email
44766350@qq.com
Country
China
ProdList
2349
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Fuxin Pharmaceutical
Tel
+86-021-021-50872116 +8613122107989
Email
contact@fuxinpharm.com
Country
China
ProdList
10000
Advantage
58
Hebei Fanbo Pharmaceutical Technology Co., Ltd.
Tel
0531-0531-88163906-805-805 15588346797
Email
fanbomedical@163.com
Country
China
ProdList
564
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Ruipu Medical Technology Co., Ltd
Tel
15895968936
Fax
qq 1018762393
Email
1018762393@qq.com
Country
China
ProdList
9999
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
More
Less

View Lastest Price from 2,3-Dihydro-1-benzofuran-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
2,3-Dihydro-1-benzofuran-2-carboxylic acid 1914-60-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

1914-60-9, 2,3-Dihydro-1-benzofuran-2-carboxylic acidRelated Search:

Tetrahydrofuran 2,5-Dihydrofuran Potassium hydrogen phthalate 2,3-Dihydrofuran 2,3-Dihydrobenzofuran Dibenzofuran Benzofuran Ascoric Acid 2-ETHOXYCARBONYL-3-COUMARANONE POLY(TETRAHYDROFURAN) STANDARD 15000 2,3-DIHYDRO-1-BENZOFURAN-5-CARBOXYLIC ACID 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-7-CARBOXYLIC ACID 2,3-Dihydro-1-benzofuran-7-carboxylic acid Trimellitic Anhydride Benzofuran-2-carboxylic acid 1,2-DIHYDRONAPHTHO[2,1-B]FURAN-2-CARBOXYLIC ACID AA 193 5-METHOXY-2,3-DIHYDRO-BENZOFURAN-2-CARBOXYLIC ACID

  • 2,3-DIHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID
  • 2,3-DIHYDRO-BENZOFURAN-2-CARBOXYLIC ACID
  • AKOS BBS-00006837
  • 2,3-Dihydro-1-Benzofurane-2-CarboxylicAcid
  • 2,3-Dihydrobenzo[b]furan-2-carboxylic acid
  • 2-Benzofurancarboxylic acid, 2,3-dihydro-
  • 2,3-Dihydro-1-benzofuran-2-carboxylic acid, 2-Carboxy-2,3-dihydrobenzo[b]furan
  • (2-methyl-3-imidazo[1,2-a]pyridinyl)methanol
  • 2,3-dihydro-1-benzofuran-2-carboxylicaci
  • 2,3-Dihydro-2-benzofurancarboxylic Acid
  • 1914-60-9
  • CARBOXYLIC ACID
  • Benzodiozoles, Benzodioxines & Benzodioxepines
  • Carboxylic Acids
  • Benzodiozoles, Benzodioxines & Benzodioxepines
  • Carboxylic Acids