4,4-dimethyl-1,4-azasilinane hydrochloride
- Product Name
- 4,4-dimethyl-1,4-azasilinane hydrochloride
- CAS No.
- 130596-62-2
- Chemical Name
- 4,4-dimethyl-1,4-azasilinane hydrochloride
- Synonyms
- 4,4-DIMETHYL-1,4-AZASILINANE HCL;4,4-dimethyl-1,4-azasilinane hydrochloride;4,4-dimethyl-4-silapiperidine hydrochloride;1-Aza-4-silacyclohexane, 4,4-dimethyl-, hydrochloride (1:1)
- CBNumber
- CB53032720
- Molecular Formula
- C6H16ClNSi
- Formula Weight
- 165.74
- MOL File
- 130596-62-2.mol
4,4-dimethyl-1,4-azasilinane hydrochloride Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C6H15NSi.ClH/c1-8(2)5-3-7-4-6-8;/h7H,3-6H2,1-2H3;1H
- InChIKey
- GAKCLWKKNFVTPB-UHFFFAOYSA-N
- SMILES
- C[Si]1(CCNCC1)C.Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D470903
- Product name
- 4,4-Dimethyl-1,4-azasilinaneHydrochloride
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 3389DT
- Product name
- 4,4-Dimethyl-1,4-azasilinanehydrochloride
- Packaging
- 100mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- A269157
- Product name
- 4,4-Dimethyl-1,4-azasilinanehydrochloride
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $79
- Updated
- 2021/12/16
- Product number
- A269157
- Product name
- 4,4-Dimethyl-1,4-azasilinanehydrochloride
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $133
- Updated
- 2021/12/16
- Product number
- A269157
- Product name
- 4,4-Dimethyl-1,4-azasilinanehydrochloride
- Purity
- 95+%
- Packaging
- 1g
- Price
- $265
- Updated
- 2021/12/16
4,4-dimethyl-1,4-azasilinane hydrochloride Chemical Properties,Usage,Production
Synthesis
130596-60-0
130596-62-2
General procedure for the synthesis of 4,4-dimethyl-1,4-azasilane hydrochloride from the compound (CAS:130596-60-0): 6N HCl (10.5 mmol) was added to an ethanol (EtOH) solution of compound 3 (2.3 g, 10.5 mmol), followed by removal of solvent under reduced pressure. The reaction mixture was co-evaporated with EtOH (2 x 10 mL) and recrystallized from a mixed EtOH-ether solvent. The ethanol solution of the resulting HCl salt was added dropwise to the slurry of Pd/C in EtOH, and the reaction was stirred for 20 h at 25 °C under hydrogen atmosphere. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and the filter cake was washed with methanol (2 x 20 mL). The filtrate was concentrated under reduced pressure to give a viscous oil, which was subsequently titrated with ether to give the final product 4 as a white solid (950 mg) in 70% yield. The synthesis of this compound was previously documented in patent WO 2006/066872.
References
[1] Patent: WO2013/54275, 2013, A1. Location in patent: Page/Page column 18-19; 22
[2] Patent: US2014/296133, 2014, A1. Location in patent: Paragraph 0075; 0092
[3] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 11, p. 1105 - 1110
[4] Patent: CN107266421, 2017, A. Location in patent: Paragraph 0094; 0095; 0096
4,4-dimethyl-1,4-azasilinane hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
4,4-dimethyl-1,4-azasilinane hydrochloride Suppliers
- Tel
- 18055517827
- sales@agilebiochem.com
- Country
- China
- ProdList
- 1003
- Advantage
- 50
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 025-025-58367986 18913956109
- Fax
- QQ:3209878052
- amy.xiang@ally-chem.com
- Country
- China
- ProdList
- 567
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 025-57027686 17372956142
- Fax
- 025-57027686
- li_lan@syntitan.com
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 021-000000 13917643586;
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9859
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 021-58581007 18019463053
- Fax
- 021-50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12878
- Advantage
- 58
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9729
- Advantage
- 58
View Lastest Price from 4,4-dimethyl-1,4-azasilinane hydrochloride manufacturers
- Product
- 4,4-dimethyl-1,4-azasilinane hydrochloride 130596-62-2
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-25