ChemicalBook > CAS DataBase List > PDE1-IN-1 (phosphate)

PDE1-IN-1 (phosphate)

Product Name
PDE1-IN-1 (phosphate)
CAS No.
1642303-38-5
Chemical Name
PDE1-IN-1 (phosphate)
Synonyms
ITI214;ITI-214 phosphate;PDE1-IN-1 (phosphate);Lenrispodun phosphate;ITI-214 phosphate salt;ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.;selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active;(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate
CBNumber
CB53041443
Molecular Formula
C29H29FN7O5P
Formula Weight
605.57
MOL File
1642303-38-5.mol
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PDE1-IN-1 (phosphate) Property

storage temp. 
Store at -20°C
solubility 
DMSO:30.0(Max Conc. mg/mL);49.54(Max Conc. mM)
form 
A solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30376
Product name
ITI214
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
30376
Product name
ITI214
Packaging
10mg
Price
$632
Updated
2024/03/01
Cayman Chemical
Product number
30376
Product name
ITI214
Packaging
5mg
Price
$356
Updated
2024/03/01
ChemScene
Product number
CS-3627
Product name
ITI-214
Purity
99.57%
Packaging
10mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
3885DW
Product name
(11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoricacid
Packaging
10mg
Price
$802
Updated
2021/12/16
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PDE1-IN-1 (phosphate) Chemical Properties,Usage,Production

Description

ITI214 is an inhibitor of phosphodiesterase 1 (PDE1; Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 μM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when administered at a dose of 50 mg/kg. ITI214 (0.1, 3, and 10 mg/kg) reverses MK-801-induced decreases in spontaneous alteration in the T-maze continuous alternation task in mice.

PDE1-IN-1 (phosphate) Preparation Products And Raw materials

Raw materials

Preparation Products

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PDE1-IN-1 (phosphate) Suppliers

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1642303-38-5, PDE1-IN-1 (phosphate)Related Search:


  • PDE1-IN-1 (phosphate)
  • ITI214
  • ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.
  • ITI-214 phosphate
  • ITI-214 phosphate salt
  • (6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate
  • selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active
  • Lenrispodun phosphate
  • 1642303-38-5