ChemicalBook > CAS DataBase List > TM38837
TM38837
- Product Name
- TM38837
- CAS No.
- 1253641-65-4
- Chemical Name
- TM38837
- Synonyms
- TM38837;CB1 antagonist 4;peripheral,Cannabinoid Receptor,TM-38837,CB1,antiobesity,TM38837,inhibit,fat,TM 38837,Inhibitor,metabolic,fear;1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-
- CBNumber
- CB53054760
- Molecular Formula
- C30H25Cl2F3N4OS
- Formula Weight
- 617.51
- MOL File
- 1253641-65-4.mol
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TM38837 Property
- Melting point:
- 171-172 °C
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 41.67 mg/mL (67.48 mM)
- pka
- 11.17±0.20(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 7131
- Product name
- TM38837
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $209
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0045262
- Product name
- TM38837
- Purity
- 99.61%
- Packaging
- 50mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0045262
- Product name
- TM38837
- Purity
- 99.61%
- Packaging
- 100mg
- Price
- $950
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0045262
- Product name
- TM38837
- Purity
- 99.61%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0045262
- Product name
- TM38837
- Purity
- 99.61%
- Packaging
- 10mg
- Price
- $200
- Updated
- 2021/12/16
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TM38837 Chemical Properties,Usage,Production
Biological Activity
TM38837 is a peripherally selective cannabinoid receptor type 1 (CB1) receptor antagonist. It has limited brain penetration to minimize or prevent CNS adverse effects and retain potential anti-obesity effects. Also it can reduces the propensity for psychotic side effects.
in vivo
TM38837 (10-100 mg/kg; po) induces a significant increase in freezing behavior at 100 mg/kg.
Animal Model: | < td class="col2"> 7-8 weeks old male C57BL/6 N mice (B6N)|
Dosage: | 10, 30, or 100 mg/kg |
Administration: | po < /td> |
Result: | High dose (100 mg/kg) induced a significant increase in freezing behavior. < /td> |
target
CB1
|
storage
Store at -20°C
TM38837 Preparation Products And Raw materials
Raw materials
Preparation Products
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TM38837 Suppliers
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View Lastest Price from TM38837 manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- TM-38837 1253641-65-4
- Price
- US $8.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-24