Bis-PEG3-PFP ester
- Product Name
- Bis-PEG3-PFP ester
- CAS No.
- 1314378-13-6
- Chemical Name
- Bis-PEG3-PFP ester
- Synonyms
- PFP-PEG3-PFP;Bis-PEG3-PFP ester;PFP-OOCCH2CH2O-PEG2-CH2CH2COO-PFP;Bis(perfluorophenyl) 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropanoate;Bis(perfluorophenyl) 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropanoate;Propanoic acid, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-, 1,1'-bis(2,3,4,5,6-pentafluorophenyl) ester;2,3,4,5,6-pentafluorophenyl 3-(2-{2-[3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propoxy]ethoxy}ethoxy)propanoate
- CBNumber
- CB53062411
- Molecular Formula
- C22H16F10O7
- Formula Weight
- 582.34
- MOL File
- 1314378-13-6.mol
Bis-PEG3-PFP ester Property
- Boiling point:
- 533.2±50.0 °C(Predicted)
- Density
- 1.509±0.06 g/cm3(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P999018
- Product name
- Bis-PEG2-PFPester
- Packaging
- 25mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 10982
- Product name
- Bis-dPEG®₃-PFPester
- Packaging
- 100mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- PEG4030
- Product name
- Pfp-PEG(3)-Pfp
- Packaging
- 100mg
- Price
- $351
- Updated
- 2021/12/16
- Product number
- LIN0000143
- Product name
- BIS-PEG3-PFP ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $430
- Updated
- 2021/12/16
- Product number
- BIPG1276
- Product name
- Bis-PEG3-PFP ester
- Packaging
- 250mg
- Price
- $468
- Updated
- 2021/12/16
Bis-PEG3-PFP ester Chemical Properties,Usage,Production
Description
Bis-PEG3-PFP ester is an amine reactive PEG linker. The two PFP ester moieties can form stable amide bonds and have been found to be very stable because they are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of the compound in aqueous envionments. Longer PEG chains tend to have enhanced water solubility properties compared to shorter PEG chains.
Uses
Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Bis-PEG3-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
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