2-CHLOROMETHYL-6-FLUOROPYRIDINE

Product Name: 2-CHLOROMETHYL-6-FLUOROPYRIDINE
CAS No.: 315180-16-6
Chemical Name: 2-CHLOROMETHYL-6-FLUOROPYRIDINE
Synonyms: CHEMPACIFIC 38174;2-CHLOROMETHYL-6-FLUOROPYRIDINE;Pyridine, 2-(chloromethyl)-6-fluoro-;Pyridine, 2-(chloromethyl)-6-fluoro- (9CI)
CBNumber: CB5306574
Molecular Formula: C6H5ClFN
Formula Weight: 145.56
MOL File: 315180-16-6.mol

More

Less

2-CHLOROMETHYL-6-FLUOROPYRIDINE Property

Boiling point:: 194.7±25.0 °C(Predicted)
Density: 1.270±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.95±0.12(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 8139BB
Product name: 2-(Chloromethyl)-6-fluoropyridine
Packaging: 1g
Price: $663
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0003231
Product name: 2-CHLOROMETHYL-6-FLUOROPYRIDINE
Purity: 95.00%
Packaging: 1G
Price: $945.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0003231
Product name: 2-CHLOROMETHYL-6-FLUOROPYRIDINE
Purity: 95.00%
Packaging: 5G
Price: $1855.51
Updated: 2021/12/16

Ambeed

Product number: A123935
Product name: 2-(Chloromethyl)-6-fluoropyridine
Purity: 97%
Packaging: 250mg
Price: $181
Updated: 2021/12/16

Chemenu

Product number: CM171581
Product name: 2-(chloromethyl)-6-fluoropyridine
Purity: 97%
Packaging: 1g
Price: $405
Updated: 2021/12/16

More

Less

2-CHLOROMETHYL-6-FLUOROPYRIDINE Chemical Properties,Usage,Production

Synthesis

407-22-7

315180-16-6

Step A: Preparation of 2-chloromethyl-6-fluoropyridine To a solution of 2-fluoro-6-methylpyridine (0.23 mL, 2.2 mmol) in acetonitrile (5 mL) was sequentially added N-chlorosuccinimide (440 mg, 3.3 mmol), benzoyl peroxide (14 mg, 0.044 mmol) and glacial acetic acid (10 μL). The reaction mixture was heated at 85 °C with stirring for 4 h, followed by continued stirring for 18 h at room temperature. Upon completion of the reaction, the mixture was partitioned between ethyl acetate and water. The organic phase was washed sequentially with water and saturated saline and dried over anhydrous magnesium sulfate. The desiccant was removed by filtration and the filtrate was concentrated under reduced pressure to give the crude product. Purification of the crude product by normal phase column chromatography (eluent: ethyl acetate/heptane) afforded 2-chloromethyl-6-fluoropyridine as a colorless oil (240 mg, 75% yield).

References

[1] Patent: US2013/143906, 2013, A1. Location in patent: Paragraph 0309
[2] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 94
[3] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 93

2-CHLOROMETHYL-6-FLUOROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-CHLOROMETHYL-6-FLUOROPYRIDINE Suppliers

China 29 Europe 1 India 1 United States 7 Global 38

Suzhou JingTong Pharmaceutical Co., Ltd.

Tel: 13675155016
Fax: 18912765016
Email: tongtf110@sina.com
Country: China
ProdList: 963
Advantage: 55

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7218
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanijing m&m biotechnology Co. ,Ltd.

Tel: 025-87782433 18021532344
Fax: 025-87782433
Email: 1345332203@qq.com
Country: China
ProdList: 4135
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Blocksynth Pharmaceutical Technology Co.,Ltd

Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5661
Advantage: 58

Shanghai Lanle Bird Industrial Co., Ltd.

Tel: 15021845385
Email: 765325601@qq.com
Country: China
ProdList: 3609
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

315180-16-6, 2-CHLOROMETHYL-6-FLUOROPYRIDINERelated Search:

2-(CHLOROMETHYL)-5-FLUOROPYRIDINE 3-(CHLOROMETHYL)-5-FLUOROPYRIDINE 2-CHLOROMETHYL-6-FLUOROPYRIDINE 2-FLUORO-6-PYRIDINECARBONYL CHLORIDE 2-Chloro-5-trifluoromethylpyridine

2-CHLOROMETHYL-6-FLUOROPYRIDINE

CHEMPACIFIC 38174

Pyridine, 2-(chloromethyl)-6-fluoro- (9CI)

Pyridine, 2-(chloromethyl)-6-fluoro-

315180-16-6

PYRIDINE