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R-268712

Product Name
R-268712
CAS No.
879487-87-3
Chemical Name
R-268712
Synonyms
2025;R-268712;CID 11703284;R 268712;R268712;R-268712, 10 mM in DMSO;4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol;1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-;2-(4-(2-fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethanol;2-(4-(2-Fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethan-1-ol;renal fibrosis,Thy1 nephritis,Transforming growth factor beta receptors,glomerulonephritis,Transforming growth factor beta,ALK tyrosine kinase receptor,HFL-1,R 268712,glomerulosclerosis,CD246,Inhibitor,Cluster of differentiation 246,UUO,Anaplastic lymphoma kinase (ALK),R268712,inhibit,TGF-β,TGF-beta/Smad,CKD,R-268712,TGF-β Receptor,Anaplastic lymphoma kinase
CBNumber
CB53126704
Molecular Formula
C20H18FN5O
Formula Weight
363.39
MOL File
879487-87-3.mol
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R-268712 Property

Boiling point:
576.8±50.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO : 125 mg/mL (343.98 mM)
pka
10.96±0.50(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
5288
Product name
R268712
Purity
≥98%(HPLC)
Packaging
10
Price
$270
Updated
2021/12/16
Tocris
Product number
5288
Product name
R268712
Purity
≥98%(HPLC)
Packaging
50
Price
$1114
Updated
2021/12/16
TRC
Product number
R990023
Product name
R268712
Packaging
50mg
Price
$1030
Updated
2021/12/16
Usbiological
Product number
256392
Product name
R 268712
Packaging
10mg
Price
$531
Updated
2021/12/16
TRC
Product number
R990023
Product name
R268712
Packaging
10mg
Price
$245
Updated
2021/12/16
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R-268712 Chemical Properties,Usage,Production

Uses

R 268712 is an orally active transforming growth factor-β type I receptor inhibitor, which prevents glomerular sclerosis in a Thy1 nephritis model.

storage

Store at -20°C

R-268712 Preparation Products And Raw materials

Raw materials

Preparation Products

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R-268712 Suppliers

China 28 United Kingdom 1 United States 6 Global 35
ShangHai Caerulum Pharma Discovery Co., Ltd.
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879487-87-3, R-268712Related Search:


  • R-268712
  • 2025
  • R 268712;R268712
  • 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanol
  • 1H-Pyrazole-1-ethanol, 4-[2-fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-
  • 2-(4-(2-Fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethan-1-ol
  • renal fibrosis,Thy1 nephritis,Transforming growth factor beta receptors,glomerulonephritis,Transforming growth factor beta,ALK tyrosine kinase receptor,HFL-1,R 268712,glomerulosclerosis,CD246,Inhibitor,Cluster of differentiation 246,UUO,Anaplastic lymphoma kinase (ALK),R268712,inhibit,TGF-β,TGF-beta/Smad,CKD,R-268712,TGF-β Receptor,Anaplastic lymphoma kinase
  • 2-(4-(2-fluoro-5-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)phenyl)-1H-pyrazol-1-yl)ethanol
  • CID 11703284
  • R-268712, 10 mM in DMSO
  • 879487-87-3