ChemicalBook > CAS DataBase List > 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one

Product Name
1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
CAS No.
1428774-45-1
Chemical Name
1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
Synonyms
EOS-61635;PF-06459988;PF-06459988 >=98% (HPLC);1-((3R,4R)-3-(((5-chloro-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one;irreversible,oral,T790M,Inhibitor,EGFR,PF 06459988,PF-06459988,HER1,NSCLC,inhibit,PF06459988,Epidermal growth factor receptor,cancer,ErbB-1;1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[(3R,4R)-3-[[[5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-
CBNumber
CB53133463
Molecular Formula
C19H22ClN7O3
Formula Weight
431.88
MOL File
1428774-45-1.mol
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1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Property

Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (115.77 mM)
form 
Solid
pka
11.26±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0017709
Product name
PF-06459988
Purity
99.49%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0017709
Product name
PF-06459988
Purity
99.49%
Packaging
10mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0017709
Product name
PF-06459988
Purity
99.49%
Packaging
25mg
Price
$290
Updated
2021/12/16
ChemScene
Product number
CS-0017709
Product name
PF-06459988
Purity
99.49%
Packaging
50mg
Price
$520
Updated
2021/12/16
ChemScene
Product number
CS-0017709
Product name
PF-06459988
Purity
99.49%
Packaging
100mg
Price
$920
Updated
2021/12/16

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Suppliers

China 27 United States 3 Global 30
Jinan elephant international trading co., LTD
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13006575422@163.com
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China
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Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 4009686088
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3193328036@qq.com
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China
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29764
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Zhongshan Geometric Biological Technology Co., Ltd.
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+86-13168912896
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China
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253
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Kaixin Chemical (Hong Kong) Limited
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010-88886666-01 13112345678
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CDXH21@126.com
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loyson@tcypharm.com
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China
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Shanghai Biopharmaleader Co., Ltd.
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+86 18721201413
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+86 (21) 5775-8967
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sales@biopharmaleader.com
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China
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1720
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Jinan Yaoyan Pharmaceutical Co., Ltd.
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jnyaoyan@163.com
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China
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3069
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312
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liming@bio-fount.com
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China
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9729
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58
Shanghai Akasaka Biotechnology Co., Ltd.
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15121162054
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CHINA
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635
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Hangzhou Synstar pharmaceutical Technology CO.,Ltd
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0571-85361029
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0571-85361029
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synstar518@163.com
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China
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1990
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1428774-45-1, 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-oneRelated Search:


  • 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
  • PF-06459988
  • EOS-61635
  • 1-((3R,4R)-3-(((5-chloro-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
  • 2-Propen-1-one, 1-[(3R,4R)-3-[[[5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-
  • PF-06459988 >=98% (HPLC)
  • irreversible,oral,T790M,Inhibitor,EGFR,PF 06459988,PF-06459988,HER1,NSCLC,inhibit,PF06459988,Epidermal growth factor receptor,cancer,ErbB-1
  • 1428774-45-1